Anti-AF-10

Anti-AF-10
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES1609.50 50 µl - -

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169.00€
ELK-ES1609.100 100 µl - -

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283.00€
 
myeloid/lymphoid or mixed-lineage leukemia, translocated to, 10(MLLT10) Homo sapiens This gene... more
Product information "Anti-AF-10"
myeloid/lymphoid or mixed-lineage leukemia, translocated to, 10(MLLT10) Homo sapiens This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010], Protein function: Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation (PubMed:26439302). [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.. Cellular localization: Nucleus .
Keywords: Anti-Protein AF-10, Anti-ALL1-fused gene from chromosome 10 protein, AF-10 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES1609

Properties

Application: WB, IHC, IF, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: The antiserum was produced against synthesized peptide derived from human AF10. AA range:211-260
MW: 109 kD
Format: Antiserum

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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