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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V5224SAF-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
1 mg/ml in 1X PBS, BSA free, sodium azide free. Adenylate cyclase is a membrane bound enzyme that... more
Product information "Anti-ADCY8 / Adenylyl cyclase 8, clone ADCY8/7341"
1 mg/ml in 1X PBS, BSA free, sodium azide free. Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase [provided by RefSeq, Jul 2008] Protein function: Catalyzes the formation of cAMP in response to calcium entry leadings to cAMP signaling activation that affect processes suche as synaptic plasticity and insulin secretion. Plays a role in many brain functions, such as learning, memory, drug addiction, and anxiety modulation through regulation of synaptic plasticity by modulating long-term memory and long-term potentiation (LTP) through CREB transcription factor activity modulation. Plays a central role in insulin secretion by controlling glucose homeostasis through glucagon- like peptide 1 and glucose signaling pathway and maintains insulin secretion through calcium-dependent PKA activation leading to vesicle pool replenishment. Also, allows PTGER3 to induce potentiation of PTGER4-mediated PLA2 secretion by switching from a negative to a positive regulation, during the IL1B induced-dedifferentiation of smooth muscle cells. [The UniProt Consortium]
Keywords: | Anti-AC8, Anti-ADCY8, Anti-Adenylyl cyclase 8, Anti-Adenylate cyclase type 8, Anti-ATP pyrophosphate-lyase 8, Anti-Adenylate cyclase type VIII, Anti-Ca(2+)/calmodulin-activated adenylyl cyclase, ADCY8 Antibody / Adenylyl cyclase 8 |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V5224SAF |
Properties
Application: | IHC (paraffin) |
Antibody Type: | Monoclonal |
Clone: | ADCY8/7341 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | A recombinant partial protein sequence (within amino acids 1-200) from the human protein |
Format: | Purified |
Database Information
KEGG ID : | K08048 | Matching products |
UniProt ID : | P40145 | Matching products |
Gene ID | GeneID 114 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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