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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R32650 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. ADAMTS4, A disintegrin and... more
Product information "Anti-ADAMTS4"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. ADAMTS4, A disintegrin and metalloproteinase with thrombospondin motifs 4, is an enzyme that in humans is encoded by the ADAMTS4 gene. ADAMTS4 is a member of the large ADAMTS family of zinc-dependent proteases. The human ADAMTS4 gene is mapped to chromosome 1 by somatic cell hybrid analysis. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. Protein function: Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-, -Ala-393' site. [The UniProt Consortium]
Keywords: | Anti-ADMP-1, Anti-ADAMTS4, Anti-ADAM-TS4, Anti-KIAA0688, Anti-ADAMTS-4, Anti-ADAM-TS 4, EC=3.4.24.82, Anti-Aggrecanase-1, Anti-A disintegrin and metalloproteinase with thrombospondin motifs 4, ADAMTS4 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R32650 |
Properties
Application: | WB, IHC (paraffin), ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Amino acids 813-837 (TPQDWLHRRAQILEILRRRPWAGRK) from the human protein |
Format: | Purified |
Database Information
KEGG ID : | K07764 | Matching products |
UniProt ID : | O75173 | Matching products |
Gene ID | GeneID 9507 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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