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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES4754.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES4754.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon... more
Product information "Anti-ACTR-IC"
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008], Protein function: Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis. [The UniProt Consortium] Recommended dilutions: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.. Cellular localization: Membrane , Single-pass type I membrane protein .
Keywords: | Anti-ALK-7, Anti-ACTR-IC, EC=2.7.11.30, Anti-Activin receptor type IC, Anti-Activin receptor type-1C, Anti-Activin receptor-like kinase 7, ACTR-IC rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES4754 |
Properties
Application: | IHC, IF, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | The antiserum was produced against synthesized peptide derived from human ACTR-1C. AA range:201-250 |
Format: | Antiserum |
Database Information
KEGG ID : | K13568 | Matching products |
UniProt ID : | Q8NER5 | Matching products |
Gene ID | GeneID 130399 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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