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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
G-PACO07204.50 | 50 µg | - |
9 - 20 business days* |
320.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
ACER1 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and... more
Product information "Anti-ACER1"
ACER1 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and for use in ELISA, WB applications. ACER1 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Endoplasmic reticulum ceramidase that catalyzes the hydrolysis of ceramides into sphingosine and free fatty acids at alkaline pH (PubMed:17713573, PubMed:20207939, PubMed:20628055). Ceramides, sphingosine, and its phosphorylated form sphingosine-1- phosphate are bioactive lipids that mediate cellular signaling pathways regulating several biological processes including cell proliferation, apoptosis and differentiation (PubMed:12783875). Exhibits a strong substrate specificity towards the natural stereoisomer of ceramides with D-erythro-sphingosine as a backbone and has a higher activity towards very long-chain unsaturated fatty acids like the C24:1-ceramide (PubMed:17713573, PubMed:20207939). May also hydrolyze dihydroceramides to produce dihydrosphingosine (PubMed:20207939, PubMed:20628055). ACER1 is a skin-specific ceramidase that regulates the levels of ceramides, sphingosine and sphingosine-1-phosphate in the epidermis, mediates the calcium-induced differentiation of epidermal keratinocytes and more generally plays an important role in skin homeostasis (PubMed:17713573). [The UniProt Consortium]
Keywords: | Anti-ASAH3, Anti-AlkCDase 1, Anti-Alkaline CDase 1, Anti-Alkaline ceramidase 1, Anti-Acylsphingosine deacylase 3, Anti-N-acylsphingosine amidohydrolase 3 |
Supplier: | Assay Genie |
Supplier-Nr: | PACO07204 |
Properties
Application: | ELISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Synthesized peptide derived from the Internal region of human ASAH3. at AA rangle: 100-180 |
Database Information
KEGG ID : | K01441 | Matching products |
UniProt ID : | Q8TDN7 | Matching products |
Gene ID | GeneID 125981 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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