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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES1567.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES1567.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC)... more
Product information "Anti-ABCD4"
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxi Protein function: Lysosomal membrane protein that transports cobalamin (Vitamin B12) from the lysosomal lumen to the cytosol in an ATP-dependent manner (PubMed:22922874, PubMed:33845046, PubMed:28572511, PubMed:31467407). Targeted by LMBRD1 lysosomal chaperone from the endoplasmic reticulum to the lysosomal membrane (PubMed:27456980). Then forms a complex with lysosomal chaperone LMBRD1 and cytosolic MMACHC to transport cobalamin across the lysosomal membrane (PubMed:25535791). [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.. Cellular localization: Endoplasmic reticulum membrane , Multi-pass membrane protein . Lysosome membrane , Multi-pass membrane protein . Targeted by LMBRD1 lysosomal chaperone to the lysosomal membrane. .
Keywords: | Anti-P70R, Anti-PMP69, Anti-PXMP1L, Anti-PXMP1-L, Anti-PMP70-related protein, Anti-Peroxisomal membrane protein 69, Anti-Peroxisomal membrane protein 1-like, Anti-Lysosomal cobalamin transporter ABCD4, Anti-ATP-binding cassette sub-family D member 4, ABCD |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES1567 |
Properties
Application: | WB, IHC, IF, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | The antiserum was produced against synthesized peptide derived from human ABCD4. AA range:111-160 |
MW: | 70 kD |
Format: | Antiserum |
Database Information
KEGG ID : | K05678 | Matching products |
UniProt ID : | O14678 | Matching products |
Gene ID | GeneID 5826 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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