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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG44070.50 | 50 µg | - | - |
6 - 14 business days* |
520.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: ATP-dependent transporter of the ATP-binding cassette (ABC) family that bind... more
Product information "Anti-ABCC3"
Protein function: ATP-dependent transporter of the ATP-binding cassette (ABC) family that bind and hydrolyze ATP to enable active transport of various substrates including many drugs, toxicants and endogenous compound across cell membranes (PubMed:11581266, PubMed:15083066, PubMed:10359813). Transports glucuronide conjugates such as bilirubin diglucuronide, estradiol-17-beta-o-glucuronide and GSH conjugates such as leukotriene C4 (LTC4) (PubMed:15083066, PubMed:11581266). Transports also various bile salts (taurocholate, glycocholate, taurochenodeoxycholate-3-sulfate, taurolithocholate- 3-sulfate). Does not contribute substantially to bile salt physiology but provides an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes. Can confers resistance to various anticancer drugs, methotrexate, tenoposide and etoposide, by decreasing accumulation of these drugs in cells (PubMed:11581266, PubMed:10359813). {ECO:0000250, UniProtKB:O88563, ECO:0000269, PubMed:10359813, ECO:0000269, PubMed:11581266, ECO:0000269, PubMed:15083066}. [The UniProt Consortium]
| Keywords: | Anti-CMOAT2, Anti-MOAT-D {ECO:0000303|PubMed:9827529}, Anti-MOAT-D {ECO:0000303|PubMed:9827529}, Anti-Multidrug resistance-associated protein 3, Anti-Multidrug resistance-associated protein 3, Anti-ATP-binding cassette sub-family C member 3, Anti-ATP-bind |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG44070 |
Properties
| Application: | FC, WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Human ABCC3 recombinant protein (Position: H22-G1351) |
| MW: | 169 kD |
| Format: | Antigen Affinity Purified |
Database Information
| KEGG ID : | K05667 | Matching products |
| UniProt ID : | O15438 | Matching products |
| Gene ID | GeneID 8714 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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