Products from Pacific Coast Bio
Pacific Coast Biologics specializes in producing animal-free growth factor proteins and cytokines for laboratory tests and pharmaceutical development. By employing state-of-the-art technologies, they offer an extensive range of high-purity cytokines, chemokines and growth factors, and excel in providing custom E. coli fermentation and recombinant protein services, beside expert consulting in protein purification and formulation, ensuring customized solutions for your scientific requirements.
More information at: www.pacificcoastbio.com
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FGF-acidic (human), animal-free recombinant
Item number: PC-AF-H-FGFAC-100UG
Product Description: FGF-acidic belongs to the extensive FGF family, comprising 23 known members. These proteins are vital in prenatal development, postnatal growth, and tissue regeneration by encouraging cellular proliferation and differentiation. FGF-acidic, specifically, is a non-glycosylated growth factor that...
| Keywords: | ECGF, FGFA, aFGF, FGF1, FGF-1, HBGF-1, Fibroblast growth factor 1, Endothelial cell growth factor, Heparin-binding growth... |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 16.8 kD |
From 40.00€
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Flt3-Ligand (human), animal-free recombinant
Item number: PC-AF-H-FLT3-100UG
Product Description: Flt3-Ligand is a growth factor responsible for regulating the proliferation of early hematopoietic cells. It binds to cells expressing the Flt3 tyrosine kinase receptor. Interestingly, Flt3-Ligand itself doesn't directly stimulate the proliferation of early hematopoietic cells. Instead, it works...
| Keywords: | Flt3L, FLT3LG, SL cytokine, Flt3 ligand, Fms-related tyrosine kinase 3 ligand, Animal-Free Recombinant Human Flt3-Ligand... |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 17.6 kD |
From 107.00€
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G-CSF (human), animal-free recombinant
Item number: PC-AF-H-GCSF-100UG
Product Description: G-CSF serves as a hematopoietic growth factor, prompting the growth of dedicated progenitor cells into neutrophils and boosting the capabilities of mature end-cells. Its production is triggered by specific signals from various cells like macrophages, fibroblasts, endothelial cells, and bone...
| Keywords: | CSF3, G-CSF, C17orf33, Filgrastim, Lenograstim, Pluripoietin, Granulocyte colony-stimulating factor, Animal-Free... |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 18.7 kD |
From 106.00€
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GDNF (human), animal-free recombinant
Item number: PC-AF-H-GDNF-100UG
Product Description: GDNF is a homodimeric neurotrophic factor connected by disulfide bonds, sharing structural similarities with Artemin, Neurturin, and Persephin. These proteins are part of the cysteine-knot superfamily of growth factors, known for their stable dimeric structures. GDNF transmits signals through a...
| Keywords: | ATF, GDNF, hGDNF, Astrocyte-derived trophic factor, Glial cell line-derived neurotrophic factor, Animal-Free Recombinant... |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 30.4 kD |
From 137.00€
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GM-CSF (human), animal-free recombinant
Item number: PC-AF-H-GMCSF-100UG
Product Description: GM-CSF, a hematopoietic growth factor, plays a role in stimulating the development of neutrophils and macrophages while also supporting the proliferation and maturation of early erythroid, megakaryocytic, and eosinophilic progenitor cells. It's primarily produced in endothelial cells, monocytes,...
| Keywords: | CSF, CSF2, GMCSF, GM-CSF, Molgramostin, Sargramostim, Colony-stimulating factor, Granulocyte-macrophage colony-stimulating... |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 14.6 kD |
From 83.00€
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Heregulin beta-1 (human), animal-free recombinant
Item number: PC-AF-H-HEREG-B-10UG
Product Description: Neuregulin/Heregulin represents a group of closely related polypeptide growth factors generated from alternate gene splicing (NRG1, NRG2, NRG3, and NRG4). Currently, there are more than 14 soluble and membrane-bound proteins derived from the NRG1 gene. The extracellular segment of transmembrane...
| Keywords: | GGF, NRG1, Animal-Free Recombinant Human Heregulin beta-1 (25 ug) |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 7.5 kD |
From 38.00€
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IGF-LR3 (human), animal-free recombinant
Item number: PC-AF-H-IFG-LR3-10UG
The IGFs, or insulin-like growth factors, are polypeptide growth factors known for their ability to stimulate the proliferation and survival of various cell types, including those found in muscle, bone, and cartilage tissue when studied in vitro. While primarily synthesized in the liver, different tissues produce...
| Keywords: | MGF, IBP1, IGF1, IGF-I, Somatomedin-C, Mechano growth factor, Insulin-like growth factor I, Animal-Free Recombinant Human... |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 9.1 kD |
From 5.00€
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IFN gamma (human), animal-free recombinant
Item number: PC-AF-H-IFN-G-100UG
Product Description: IFN-gamma, an acid-labile interferon, is produced by CD4 and CD8 T lymphocytes as well as activated NK cells. Its receptors are widespread in immune cells, triggering an increase in class I MHC protein surface expression upon IFN-gamma signaling. This enhancement aids in antigen presentation to...
| Keywords: | IFNG, IFN-gamma, Interferon gamma, Immune interferon, Animal-Free Recombinant Human IFN gamma (25 ug) |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 16.8 kD |
From 26.00€
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IGF-1 (human), animal-free recombinant
Item number: PC-AF-H-IGF1-100UG
The IGFs are polypeptide growth factors with mitogenic properties, stimulating cell proliferation and survival in various tissues like muscle, bone, and cartilage when studied in vitro. Although primarily produced in the liver, different tissues produce IGFs at specific times. Belonging to the Insulin gene family,...
| Keywords: | MGF, IBP1, IGF1, IGF-I, Somatomedin-C, Mechano growth factor, Insulin-like growth factor I, Animal-Free Recombinant Human... |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 7.6 kD |
From 78.00€
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IGF-2 (human), animal-free recombinant
Item number: PC-AF-H-IGF2-100UG
IGFs, or insulin-like growth factors, are polypeptide growth factors known for their ability to stimulate the proliferation and survival of various cell types, including those found in muscle, bone, and cartilage tissue when studied in vitro. They are primarily synthesized in the liver, though various tissues...
| Keywords: | IGF2, PP1446, Animal-Free Recombinant Human IGF-2 (250 ug) |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 7.5 kD |
From 38.00€
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IL-17 (human), animal-free recombinant
Item number: PC-AF-H-IL-17-100UG
Product Description: Originally identified as IL-17 and now referred to as IL-17A, this protein is a homodimer consisting of two 136 amino acid chains. It is released by activated T-cells and acts on stromal cells, triggering the production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17...
| Keywords: | CTLA8, IL17A, IL-17, IL-17A, CTLA-8, Interleukin-17A, Cytotoxic T-lymphocyte-associated antigen 8, Animal-Free Recombinant... |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 31.3 kD |
From 78.00€
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IL-1 alpha (human), animal-free recombinant
Item number: PC-AF-H-IL1-A-100UG
Product Description: IL-1alpha is a proinflammatory cytokine that is not secreted, it is produced by various cells like monocytes, tissue macrophages, keratinocytes, and other epithelial cells. Both IL-1alpha and IL-1beta bind to the same receptor and share similar, if not identical, biological properties. These...
| Keywords: | IL1A, IL1F1, IL-1 alpha, Hematopoietin-1, Interleukin-1 alpha, Animal-Free Recombinant Human IL-1 alpha (25 ug) |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 18 kD |
From 107.00€
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