PKCalpha (C2-4) Inhibitor Peptide

The C2 domain of conventional PKC isoforms mediates calcium-dependent translocation. Peptides from that region can block PKC translocation and inhibit function, both in cells and cell lysates. PKCalpha (C2-4) inhibitor peptide is a synthetic peptide that blocks PKC activity in HepG2 cells stimulated with calcium and pancreastatin when applied at 10 µM.Synonyms: Protein Kinase Calpha (C2-4) Inhibitor Peptide. Molecular Formula: C47H74N14O17. Formula Weight: 1107.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 1 mg/ml, DMSO: 10 mg/ml, PBS (pH 7.2): 5 mg/ml. SMILES: O=C[C@H](CO)NN[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N1CCC[C@H]1C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@]([C@@H](C)O)([H])C=O)=O)=O)=O)CC2=CC=C(O)C=C2)=O)=O)=O)=O. InChi Code: InChI=1S/C47H74N14O16/c1-24(2)18-33(60-59-27(21-62)22-63)44(75)57-34(20-38(49)68)46(77)61-17-5-7-36(61)45(76)55-31(13-15-39(69)70)41(72)56-32(19-26-8-10-28(66)11-9-26)43(74)53-29(6-4-16-52-47(50)51)40(71)54-30(12-14-37(48)67)42(73)58-35(23-64)25(3)65. InChi Key: XYGZNIKBSICVGI-FZSOQVDMSA-N.