- Search results for K02677
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151 products were found matching "K02677"!
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Item number: Cay10008014-1
Phorbol 12-myristate 13-acetate (PMA), also known as 12-O-tetradecanoylphorbol 13-acetate (TPA), is a phorbol ester and PKC activator. It activates the PKC isoforms PKCalpha, -beta, -gamma, -delta, -epsilon, -eta, and -theta but not PKCzeta or -iota/lambda. PMA (1-10 ng/ml) induces NF-kappaB-dependent gene...
Keywords: | 12-O-Tetradecanoylphorbol-13-acetate, PMA, TPA, tetradecanoic acid,... |
Application: | PKC activator |
CAS | 16561-29-8 |
MW: | 616.8 D |
From 50.00€
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Item number: AG-CN2-0010-M001
Most commonly-used phorbol ester, Binds to and activates protein kinase C (PKC) at nM concentrations, Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors...
Keywords: | PMA, TPA, 12-O-Tetradecanoylphorbol 13-acetate |
Application: | PKC activator |
CAS | 16561-29-8 |
MW: | 616,8 D |
From 44.00€
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Item number: LKT-S7600.1
A protein kinase C inhibitor which induces apoptosis in many cell types. Experimental results obtained in a cell -free assay suggest that cytoplasmic proteins directly modulated by staurosporine may be involved in signaling the induction of DNA fragmentation and apoptosis.
Keywords: | AM-2282, STS |
Application: | PKC inhibitor |
CAS | 62996-74-1 |
MW: | 466,5 D |
From 60.00€
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Item number: Cay40149-1
[pGlu4]-Myelin basic protein peptide is a substrate for PKC. It is selectively phosphorylated by PKC over PKA and phosphorylase kinase.Formal Name: 5-oxo-L-prolyl-L-lysyl-L-arginyl-L-prolyl-L-seryl-L-glutaminyl-L-arginyl-L-seryl-L-lysyl-L-tyrosyl-L-leucine, trifluoroacetate salt. Synonyms: [pGlu4]-MBP Peptide....
Keywords: | [pGlu4]-MBP Peptide,... |
Application: | PKC peptide substrate |
MW: | 1373.6 D |
From 34.00€
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Item number: Cay81590-1
Staurosporine (Stsp) is potent inhibitor of protein kinase C (PKC) from rat brain, exhibiting an IC50 value of 2.7 nM. It inhibits rat recombinant PKC-alpha approximately 100- and 1,000-fold better than PKC-delta and PKC-zeta, respectively. However, Stsp is non-selective in that it also inhibits the activity of a...
Keywords: | Stsp,... |
Application: | PKC inhibitor |
CAS | 62996-74-1 |
MW: | 466.5 D |
From 43.00€
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Item number: NSJ-F54980-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. PRKCA is a calcium-activated, phospholipid-dependent, serine-and threonine-specific enzyme. It may play a role in cell motility by phosphorylating CSPG4. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the...
Keywords: | Anti-PKCA, Anti-PKC-A, Anti-PRKCA, Anti-PKC-alpha, Anti-Protein kinase C alpha type, PRKCA Antibody / PKC alpha |
Application: | IF, FC, IHC (paraffin), WB |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 326.00€
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Item number: ELK-ELK3257.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PKCa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PKCa. Next,...
Keywords: | Pkca, Prkca, PKC-A, PKC-alpha, EC=2.7.11.13, Protein kinase C alpha type |
Application: | ELISA |
Species reactivity: | mouse |
From 365.00€
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Item number: ELK-ELK4684.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PKCa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PKCa. Next,...
Keywords: | PKCA, PRKCA, PKC-A, PKC-alpha, Protein kinase C alpha type |
Application: | ELISA |
Species reactivity: | human |
From 365.00€
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Item number: ELK-ES6761.100
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members...
Keywords: | Anti-phospho-PKCA, Anti-phospho-PKC-A, Anti-phospho-PRKCA, Anti-phospho-PKC-alpha, Anti-phospho-Protein kinase C alpha... |
Application: | WB, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 169.00€
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Item number: ELK-ES6762.100
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members...
Keywords: | Anti-phospho-PKCA, Anti-phospho-PKC-A, Anti-phospho-PRKCA, Anti-phospho-PKC-alpha, Anti-phospho-Protein kinase C alpha... |
Application: | WB, IHC, IF, ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 169.00€
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Item number: ELK-ES6764.100
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members...
Keywords: | Anti-PKCA, Anti-PKC-A, Anti-PRKCA, Anti-PKC-alpha, Anti-Protein kinase C alpha type, PKC alpha rabbit pAb |
Application: | WB, IHC, IF, ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 169.00€
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Item number: AG-CN2-0022-M001
Isolated from Streptomyces spiralis. Antibiotic. Antifungal and anti-yeast activity. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-induced platelet aggregation. Potent, cell permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases. Inhibits protein...
Keywords: | Antibiotic AM2282, Antibiotic 230, CCRIS 3272 |
Application: | Protein kinase inhibitor, Apoptosis inducer |
CAS | 62996-74-1 |
MW: | 466,5 D |
From 50.00€
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