Other Peptides

3,3',5'-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRalpha and TRbeta than 3,3',5-triiodo-L-thyronine (Cay-16028) and commonly described as inactive. However, high...

Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two...

Glucagon is a peptide hormone produced from proglucagon in pancreatic alpha cells that has a role in the regulation of glucose metabolism. Pulsatile application of glucagon to rat hepatocytes stimulates glucose production ex vivo. It also stimulates glucose output from perfused rat livers via increases in...

Tentoxin is a cyclic tetrapeptide first isolated from the plant pathogen A. alternata. It is an herbicide that inhibits chloroplast development, resulting in chlorotic tissue. Tentoxin is selectively phytotoxic, as it kills a number of important weeds at concentrations that have no effects on several important...

L-Leucyl-L-Leucine methyl ester (LLME) is a lysosomal condensation product that has been reported to be cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes without affecting helper T cells and B cells. It has also been shown to induce death of monocytes, polymorphonuclear leukocytes, and myeloid...

Description: Substance P acetate is a peptide mainly secreted by neurons and is involved in many biological processes including nociception and inflammation. Substance P acetate is a neuroinflammatory factor that can act as a neurotransmitter and neuromodulator in the central nervous system and can be used to study...

Description: N-Acetylcarnosine (N-Acetyl-L-carnosine) is thought to be able to combat some of the effects of oxidative stress as it has anti-oxidant properties. Target: Others. Smiles: CC(=O)NCCC(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O. References: Babizhayev MA, et al. N-Acetylcarnosine, a natural histidine-containing...

Description: Fmoc-N-Me-Ala-OH is available for the peptide-coupling reaction. Target: Others, Amino Acids and Derivatives. Smiles: C[C@H](N(C)C(=O)OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)C(O)=O. References: Harris KS, et al. Rapid optimization of a peptide inhibitor of malaria parasite invasion by comprehensive N-methyl...

Description: [Gln144]-PLP(139-151) is an experimental antigen employed to investigate the cross-reactivity of T cells to self and non-self antigens. It activates T cells by binding to the T-cell Receptor (TCR), initiating an immune response. It is useful in the study of autoimmune disease regulation. Smiles:...

Description: HBP08 is a selective inhibitor that disrupts the interaction between CXCL12 and HMGB1. It demonstrates a high affinity for HMGB1 with a dissociation constant (K d) of 0.8 µM and effectively inhibits cell migration induced by CXCL12. Smiles:...

Description: p53 (232-240), a peptide derived from the 232-240 amino acid sequence of the human tumor suppressor protein p53, improves its binding affinity to the Major Histocompatibility Complex (MHC). This enhancement increases the immunogenicity of the peptide, boosting the immune system's response to tumor...

Description: WEYIPNV is a ligand of SurA, specifically binding to the P1 domain of SurA (Kd: 1-14 µM). Its binding facilitates the release of the P1 domain from the core domain. Smiles:...