Other Peptides

3,3',5'-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRalpha and TRbeta than 3,3',5-triiodo-L-thyronine (Cay-16028) and commonly described as inactive. However, high...

Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two...

Glucagon is a peptide hormone produced from proglucagon in pancreatic alpha cells that has a role in the regulation of glucose metabolism. Pulsatile application of glucagon to rat hepatocytes stimulates glucose production ex vivo. It also stimulates glucose output from perfused rat livers via increases in...

Tentoxin is a cyclic tetrapeptide first isolated from the plant pathogen A. alternata. It is an herbicide that inhibits chloroplast development, resulting in chlorotic tissue. Tentoxin is selectively phytotoxic, as it kills a number of important weeds at concentrations that have no effects on several important...

L-Leucyl-L-Leucine methyl ester (LLME) is a lysosomal condensation product that has been reported to be cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes without affecting helper T cells and B cells. It has also been shown to induce death of monocytes, polymorphonuclear leukocytes, and myeloid...

Myelin oligodendrocyte glycoprotein (MOG) (92-106) is an encephalitogenic peptide and a peptide fragment of MOG, a protein involved in demyelinating CNS disorders. MOG (92-106) induces relapsing-remitting experimental autoimmune encephalomyelitis (RR-EAE) in SJL/J mice that lack NK1.1+ T cells and express a Th2-low...

CAQK targeting/delivery peptide (CAQK peptide) is a four-amino acid synthetic peptide that interacts with versican and tenascin-R, proteoglycans that are upregulated in the brain extracellular matrix (ECM) in CNS injuries. Intravenous administration of CAQK peptide leads to its accumulation in injured brain tissue...

Mc-Ala-Ala-PAB is a peptide linker molecule that has been used in the synthesis of antibody-drug conjugates (ADCs). It contains a maleimidocaproyl (Mc) group that can be conjugated to an antibody and a p-aminobenzyl (PAB) spacer that allows the peptide to be linked to active compounds. Mc-Ala-Ala-PAB has been used...

Tripeptide-41 is a cosmeceutical peptide.. SMILES: OC(C=C1)=CC=C1C[C@@H](C(O)=O)NC([C@@H](NC([C@@H](N)CC2=CC=CC=C2)=O)CC3=CNC4=CC=CC=C34)=O.OC(C)=O. InChi Code:...

Oligopeptide-20 is a peptide that corresponds to amino acids 55-66 of mature insulin-like growth factor 1 (IGF-1). It increases growth of keratinocytes and fibroblasts and the levels of procollagen, laminin, and fibronectin in keratinocytes. Oligopeptide-20 (100 mg/animal), as part of a peptide nanosome-based skin...

Acetyl hexapeptide-49 is an antagonist of proteinase-activated receptor 2 (PAR2). It inhibits PAR2 agonist-induced calcium release and calcitonin gene-related peptide (CGRP) and IL-6 production in human keratinocytes. Acetyl hexapeptide-49 also induces proliferation in human keratinocytes and has photoprotective...

Diaminopropionyl tripeptide-33 is a peptide containing alanine, proline, and histidine and modified with a 2,3-diaminopropionyl (DAP) group.. SMILES: C[C@H](NC(C(N)CN)=O)C(N1CCC[C@H]1C(N[C@H](C(O)=O)CC2=CN=CN2)=O)=O.CC(O)=O. InChi Code:...