Other Peptides

3,3',5'-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRalpha and TRbeta than 3,3',5-triiodo-L-thyronine (Cay-16028) and commonly described as inactive. However, high...

Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two...

Glucagon is a peptide hormone produced from proglucagon in pancreatic alpha cells that has a role in the regulation of glucose metabolism. Pulsatile application of glucagon to rat hepatocytes stimulates glucose production ex vivo. It also stimulates glucose output from perfused rat livers via increases in...

Tentoxin is a cyclic tetrapeptide first isolated from the plant pathogen A. alternata. It is an herbicide that inhibits chloroplast development, resulting in chlorotic tissue. Tentoxin is selectively phytotoxic, as it kills a number of important weeds at concentrations that have no effects on several important...

L-Leucyl-L-Leucine methyl ester (LLME) is a lysosomal condensation product that has been reported to be cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes without affecting helper T cells and B cells. It has also been shown to induce death of monocytes, polymorphonuclear leukocytes, and myeloid...

TX0136 is a peptide corresponding to amino acids 196-204 of centromere protein I (CENP-1).. SMILES: C[C@@H](C(N[C@H](C(N[C@@H](CS[H])C(N1CCC[C@H]1C(N[C@@H](CC2=CC=C(O[H])C=C2)C(N[C@@H](C(C)C)C(N[C@@H](CS[H])C(N[C@@H](CC3=CN([H])C=N3)C(N[C@H](C(O)=O)CC(C)C)=O)=O)=O)=O)=O)=O)=O)CC(C)C)=O)N[H].O=C(O)C(F)(F)F. InChi...

KLQEFLQTL is a peptide corresponding to amino acids 16-24 of Fanconi anemia group I protein (FACI). SMILES:...

DNAJ-PKAc peptide is a synthetic peptide spanning the junction of the DNAJ-PKAc fusion protein found in fibrolamellar carcinoma (FLC) tumors. It contains amino acids 59-70 of DNAJ heat shock protein family member B1 (DNAJB1) and 16-27 of PKAalpha, which are located in the J domain and catalytic domain,...

DC-2 peptide is a synthetic peptide that contains a DHHC palmitoylation motif. It reduces H-Ras cell membrane localization in HeLa cells and increases ERK and Akt phosphorylation in SW480 colorectal cancer cells with high EGFR expression but not in SW620 colorectal cancer cells with low EGFR expression. DC-2 reduces...

Shearamide A is a cyclic octapeptide that has been found in E. shearii and has antiinsectan activity. It reduces the growth rate of H. zea larvae by 35% when administered in the diet at 100 ppm.. SMILES:...

TX0121 is a peptide corresponding to amino acids 201-209 of centromere protein I (CENP-1).. SMILES:...

TX-139 is a peptide corresponding to amino acids 343-351 of centromere protein I (CENP-I).. SMILES: O=C(N[C@H](C(N[C@@H](CCC(N[H])=O)C(N[C@@H](CO[H])C(N[C@H](C(N1CCC[C@H]1C(N[C@@H](CCC(N[H])=O)C(N[C@H](C(N[C@H](C(O)=O)CC(C)C)=O)CC(C)C)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)CC(C)C)[C@H](CCC(N[H])=O)N[H].FC(F)(C(O)=O)F. InChi...