Other Peptides

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MOTS-c (human)
MOTS-c (human)

Item number: AG-CP3-0026-M001

Solid lyophilized powder. Soluble in water. Mitochondria-derived peptide (MDP), Promotes biosynthesis of the endogenous AMP analog AICAR and consequently AMP-activated protein kinase (AMPK), Induces cellular and systemic glucose uptake and improves insulin sensitivity. Shown to prevent diet-induced obesity (DIO) in mice, Potential anti-obesity and anti-aging compound.
Application: Mitochondria-derived peptide, AMPK promoter
CAS 1627580-64-6
MW: 2288,6 D
Purity: >95%
Format: Solid
From 165.00€
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Thiostrepton
Thiostrepton

Item number: Cay19200-500

The mammalian transcription factor forkhead box M1 (FoxM1) is induced during G1 phase, with expression continuing through S phase and mitosis. Thiostrepton is a natural peptide thiazole antibiotic that inhibits FoxM1 in mammalian cells, preventing the expression of FoxM1-regulated genes, which includes FoxM1 itself. Through this mechanism, thiostrepton prevents proliferation...
Application: FoxM1 inhibitor
CAS 1393-48-2
MW: 1664.9 D
Purity: >95%
Format: Solid
From 57.00€
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Malformin C
Malformin C

Item number: Cay21613-1

Malformin C is a natural fungus-derived bicyclic pentapeptide that has antibacterial properties, particularly against species of Bacillus. Malformin C potently blocks the ability of bleomycin (Cay-13877) to induce G2 arrest in human T-cell leukemia-derived Jurkat cells (IC50 = 0.9 nM). It less potently abrogates colchicine-induced M phase arrest in Jurkat cells (IC50 = 24...
Application: Antibacterial
CAS 59926-78-2
MW: 529.7 D
Purity: >95%
Format: Solid
From 124.00€
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AAF-CMK (trifluoroacetate salt)
AAF-CMK (trifluoroacetate salt)

Item number: Cay14461-5

Tripeptidyl peptidase II (TPPII) is a serine peptidase of the subtilisin-type which removes tripeptides from the free NH2 terminus of oligopeptides. AAF-CMK is an irreversible inhibitor of TPPII commonly used at 10-100 µM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome. AAF-CMK also inhibits bleomycin hydrolase and...
Application: TPPII inhibitor, Bleomycin hydrolase and aminopeptidase inhibitor
CAS 184901-82-4
MW: 453.8 D
Purity: >95%
Format: Crystalline Solid
From 62.00€
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Iberiotoxin
Iberiotoxin

Item number: Cay14608-100

Iberiotoxin, a peptide purified from venom of the scorpion B. tamulus, is a selective blocker of large-conductance calcium ion-activated potassium ion channels (BKCa). In single channel recordings, iberiotoxin can reversibly block outward currents mediated by BKCa in excised membrane patches from bovine aortic smooth muscle with an IC50 value of 250 pM. It is also a...
Application: BKCa blocker
CAS 129203-60-7
MW: 4230.9 D
Purity: >95%
Format: Solid
249.00€
Review
Apamin
Apamin

Item number: Cay17082-500

Apamin is an 18 amino acid peptide toxin found in bee venom. It is a potent blocker of small conductance Ca2+-activated K+ (SK, KCa2) channels that is more effective at SK2 than SK1 and SK3 (IC50 values are 0.06-0.4, 1-12, and 1-13 nM, respectively). It is ineffective against SK4 at 1 µM. Apamin is used to elucidate the roles of these channels in cells and tissues expressing...
Application: Bee venom toxin, KCa2 blocker
CAS 24345-16-2
MW: 2027.3 D
Purity: >95%
Format: Solid
157.00€
Review
A-54556B
A-54556B

Item number: Cay17090-500

A-54556B is a natural acyldepsipeptide (ADEP) antibiotic isolated from the fermentation broth of S. hawaiiensis. Like the closely related ADEP, A-54556A (Cay-15305), A-54556B is effective against Gram-positive bacteria, including penicillin-resistant S. aureus. A-54556B is also effective against many strains of anaerobic bacteria.
Application: Gram-positive bacterial antibiotic
CAS 1629166-56-8
MW: 704.8 D
Purity: >95%
Format: Solid
From 325.00€
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Enopeptin A
Enopeptin A

Item number: Cay17092-500

Enopeptin A, originally isolated from a culture broth of Streptomyces sp. RK-1051, is a depsipeptide antibiotic that contains two unusual amino acids (N-methylalanine and 4-methylproline) and features a pentaenone side chain. It is effective against Gram-positive bacteria, including methicillin-resistant S. aureus (MIC = 25 µg/ml), and Gram-negative bacteria, including...
Application: Gram-positive bacterial antibiotic
CAS 139601-96-0
MW: 896 D
Purity: >95%
Format: Solid
From 374.00€
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Micrococcin P1
Micrococcin P1

Item number: Cay17093-500

Micrococcin P1 is a macrocyclic peptide antibiotic that functions as an acceptor-site-specific inhibitor of ribosomal protein synthesis, effectively preventing the growth of Gram-positive bacteria without affecting that of Gram-negative bacteria.
Application: Gram-positive bacterial antibiotic
CAS 67401-56-3
MW: 1144.4 D
Purity: >95%
Format: Solid
From 394.00€
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Pyridomycin
Pyridomycin

Item number: Cay17095-500

Pyridomycin is a structurally unusual antimycobacterial cyclodepsipeptide whose composition includes two rare moieties: 3-(3-pyridyl)-L-alanine and 2-hydroxy-3-methylpent-2-enoic acid. It inhibits NADH-dependent enoyl (Acyl-Carrier-Protein) reductase InhA, preventing mycolic acid synthesis in M. tuberculosis, including isoniazid-resistant strains (MICs = 0.31-0.63 µg/ml).
Application: Antimycobacterial enoyl ACP reductase inhA inhibitor
CAS 18791-21-4
MW: 540.6 D
Purity: >95%
Format: Solid
From 374.00€
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alpha-Amanitin
alpha-Amanitin

Item number: Cay17898-1

alpha-Amanitin is a cyclic peptide found in several species of the Amanita genus as well as other poisonous fungi. At 1, 10, and 50 µg/ml, respectively, alpha-amanitin inhibits RNA polymerase II, III, and IV, preventing translocation of the enzymes on DNA, which significantly slows the rate of transcription. RNA polymerase I is insensitive to its effects. This toxin is used...
Application: RNA polymerase inhibitor
CAS 23109-05-9
MW: 919 D
Purity: >90%
Format: Crystalline Solid
219.00€
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Phalloidin
Phalloidin

Item number: Cay18039-1

Phalloidin is a natural mycotoxin first isolated from the death cap mushroom, A. phalloides. It binds F-actin and stabilizes actin fibers. Fluorescently labeled phalloidin is commonly used to stain F-actin in cells.
Application: Actin fiber stabilizer
CAS 17466-45-4
MW: 788.9 D
Purity: >98%
Format: Crystalline Solid
199.00€
Review
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