Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10008822-1 1 mg -

1 - 10 business days

Cay10008822-5 5 mg -

1 - 10 business days

Cay10008822-10 10 mg -

1 - 10 business days

Cay10008822-25 25 mg -

1 - 10 business days

Bortezomib is a dipeptide boronic acid derivative that reversibly inhibits the 20S proteasome (Ki... more
Product information "Bortezomib"
Bortezomib is a dipeptide boronic acid derivative that reversibly inhibits the 20S proteasome (Ki = 0.6 nM). It binds the beta5-subunit of the 20S proteasome and selectively inhibits chymotryptic activity. In part by blocking the degradation of tumor-suppressing and proapoptotic proteins, bortezomib drives cell cycle arrest and apoptosis in cancer cell lines and has applications in multiple myeloma and certain lymphomas, as well as other types of cancer. Proteasome inhibitors, including bortezomib, have potential in combination therapy with chemotherapy and radiation therapy against cancer.
Keywords: LDP-341, MG-341, MLN341, NSC 681239, PS-341, Velcade, B-[(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]-boronic acid
Supplier: Cayman Chemical
Supplier-Nr: 10008822-1


Application: Proteasome subunit beta type-1/5 inhibitor
Conjugate: No
MW: 384.2 D
Formula: C19H25BN4O4
Purity: >95%
Format: Crystalline Solid

Database Information

CAS : 179324-69-7| Search using CAS
KEGG ID : K02732 | Search using KEGG ID

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H300, H315, H319, H361, H372, H411
P Phrases: P201, P202, P260, P264, P270, P273, P280, P314, P321, P330, P391, P301+P310, P302+P352, P305+P351+P338, P308+P313, P332+P313, P337+P313, P362+P364, P405, P501
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Bortezomib"
Write a review
or to review a product.