41 products were found matching "K02732"!

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Psmb1 (Proteasome subunit beta type 1) is a critical structural component of the 20S core particle within the proteasome complex. The proteasome is essential for the regulated degradation of intracellular proteins, particularly those tagged with ubiquitin. Psmb1...

Bortezomib is a dipeptide boronic acid derivative that reversibly inhibits the 20S proteasome (Ki = 0.6 nM). It binds the beta5-subunit of the 20S proteasome and selectively inhibits chymotryptic activity. In part by blocking the degradation of tumor-suppressing and proapoptotic proteins, bortezomib drives cell...

Proteasome inhibitor.

Lyophilized powder. Soluble in DMSO. Z-LLE-AMC is a fluorogenic peptide substrate for measuring caspase-like activity of the proteasome. Hydrolysis of this substrate by the beta1-subunit of the 20S proteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at 445nm. This...

Protein function: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome...

Synthetic. Chemical. CAS: 1624602-30-7. Formula: C19H16ClN5O6S. MW: 477.9. Synthetic. Potent selective and reversible chloroquine derivative 20S proteasome inhibitor (all proteolytic subunits). Targets the trypsin-like beta2 subunit of the constitutive 20S proteasome (IC50=1nM). Cross-reacts and inhibits the...

K-7174 is a 20S proteasome inhibitor. It inhibits the beta1, beta2, and beta5 catalytic subunits of the 20S proteasome when used at a concentration of 5 µM. K-7174 (10 µM) reduces TNF-alpha- or IL-1beta-induced adherence of U937 monocytes to human umbilical vein endothelial cells (HUVECs) in a co-culture model of...

Protein function: Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the...

Protein function: Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Proteasome subunit beta type-1 also known as 20S proteasome subunit beta-6 (based on systematic nomenclature) is a protein that in humans is encoded by the PSMB1 gene. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human proteasome. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human...

Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: PSMB1. Antigen Species: Human