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Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay17601-5 5 mg -

1 - 10 business days

Cay17601-10 10 mg -

1 - 10 business days

Cay17601-25 25 mg -

1 - 10 business days

Cay17601-50 50 mg -

1 - 10 business days

Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades... more
Product information "MeOSuc-AAPV-pNA"
Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neutrophil elastase is a serine proteinase that is secreted by neutrophils during inflammation to destroy pathogens. Evaluating these enzymes is helpful to understanding inflammatory autoimmune processes. MeOSuc-AAPV-pNA is a highly sensitive peptide substrate that is hydrolyzed by both human and mouse neutrophil elastase and PR3, but not cathepsin G or chymotrypsin. Enzyme activity can be quantified by colorimetric detection of free p-nitroanilide at 405 nm.
Keywords: N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-L-valinamide
Supplier: Cayman Chemical
Supplier-Nr: 17601-5


Application: Neutrophil elastase & PR3 substrate
Conjugate: No
MW: 590.6 D
Formula: C27H38N6O9
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 70967-90-7| Find alternatives
KEGG ID : K01327 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Our products are for laboratory research use only: Not for administration to humans!
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