- Search results for K01327
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79 products were found matching "K01327"!
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Item number: Cay600610-192
Cayman's Neutrophil Elastase Activity Assay kit employs a specific non-fluorescent elastase substrate, (Z-Ala-Ala-Ala-Ala)2Rh110, which is selectively cleaved by elastase to yield the highly fluorescent compound R110. Fluorescence can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525...
Keywords: | HLE, ELA2, ELANE, Elastase-2, Medullasin, EC=3.4.21.37, PMN elastase, Neutrophil elastase, Human leukocyte elastase, Bone... |
Application: | Neutrophile elastase detection |
Species reactivity: | human |
543.00€
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Item number: ELK-ELK1701.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ELA2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ELA2. Next,...
Keywords: | HLE, ELA2, ELANE, Elastase-2, Medullasin, PMN elastase, Neutrophil elastase, Human leukocyte elastase, Bone marrow serine... |
Application: | ELISA |
Species reactivity: | human |
From 365.00€
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Item number: ELK-ELK2332.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse ELA2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse ELA2. Next,...
Keywords: | Ela2, Elane, Elastase-2, EC=3.4.21.37, Leukocyte elastase, Neutrophil elastase |
Application: | ELISA |
Species reactivity: | mouse |
From 365.00€
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Item number: Cay17601-10
Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neutrophil elastase is a serine proteinase that is secreted by neutrophils during inflammation to...
Keywords: | N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-L-valinamide |
Application: | Neutrophil elastase & PR3 substrate |
CAS | 70967-90-7 |
MW: | 590.6 D |
From 43.00€
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Item number: BPS-82090-1
The Neutrophil Elastase Inhibitor Screening Assay Kit is a fluorogenic assay designed to measure the activity of elastase for screening and profiling applications. The elastase assay kit comes in a convenient 96-well or 384-well format and contains enough purified elastase, fluorochrome-conjugated substrate, and...
Keywords: | HLE, ELA2, ELANE, Elastase-2, Medullasin, PMN elastase, Neutrophil elastase, Human leukocyte elastase, Bone marrow serine... |
Application: | Small molecule inhibitor screening, HTS |
Species reactivity: | human |
From 767.00€
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Item number: Cay11675-1
(Z-Ala-Ala-Ala-Ala)2Rh110 is a sensitive fluorogenic elastase substrate. The colorless and nonfluorescent (Z-Ala-Ala-Ala-Ala)2Rh110 is selectively cleaved by elastase to yield the highly fluorescent compound rhodamine 110, which can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525...
Keywords: | (Z-Ala-Ala-Ala-Ala)2Rhodamine110, bis-(CBZ-L-alanyl-L-arginine amide) Rhodamine 110,... |
Application: | Elastase substrate |
CAS | 149695-85-2 |
MW: | 1167.2 D |
From 58.00€
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Item number: Cay17779-50
Sivelestat is an inhibitor of neutrophil elastase (IC50 = 44 nM for the human enzyme). It is selective for neutrophil elastase over trypsin, thrombin, plasmin, kallikrein, chymotrypsin, and cathepsin G at 100 µM. Sivelestat inhibits the formation of neutrophil extracellular traps (NETs) induced by ionomycin...
Keywords: | LY544349, ONO-5046, 4-[[[2-[[(carboxymethyl)amino]carbonyl]phenyl]amino]sulfonyl]phenyl ester 2,2-dimethyl-propanoic acid,... |
Application: | Elastase inhibitor |
CAS | 201677-61-4 |
MW: | 528.5 D |
From 84.00€
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Item number: AG-CR1-3632-M005
Solid. Soluble in DMSO or water. Potent, selective intracellular neutrophil elastase (NE, alpha-1-proteinase) inhibitor (by covalently binding to NE), Inhibits human neutrophil elastase (HNE) and is selective over other human serine proteases with IC50 values of 22nM for HNE, >,100µ,M for trypsin, cathepsin G and...
Keywords: | (3S,3aS,6aR)-3-Isopropyl-1-(methylsulfonyl)-4-((E)-4-(piperidin-1-yl)but-2-enoyl)hexahydropyrrolo[3,2-b]pyrrol-2(1H)-one |
Application: | Potent selective intracellular neutrophil elastase (NE alpha-1-proteinase) inhibitor |
CAS | 197890-44-1 |
MW: | 434,0 D |
From 72.00€
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Item number: Cay21194-5
3,4-Dichloroisocoumarin (3,4-DCI) is a serine protease inhibitor. It completely inhibits enzyme activity of 24 serine proteases including human leukocyte elastase, thrombin, plasmin, Factor Xa, and Factor XIIa in vitro. 3,4-DCI stimulates caseinolytic activity of bovine pituitary multicatalytic proteinase complex...
Keywords: | 3,4-DCI, 3,4-dichloro-1H-2-benzopyran-1-one |
Application: | Irreversible Granzyme / cathepsin G / neutrophil elastase inhibitor |
CAS | 51050-59-0 |
MW: | 215 D |
From 43.00€
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Item number: Cay14922-5
Neutrophil elastase is stored within cytoplasmic azurophilic granules in the neutrophil and released upon stimulation by pathogens where it acts either as free protein or is associated with neutrophil extracellular traps (NETs). Together with other proteases released from activated neutrophils, neutrophil elastase...
Keywords: | 1-(3-methylbenzoyl)-1H-indazole-3-carbonitrile |
Application: | ELANE inhibitor |
CAS | 1448314-31-5 |
MW: | 261.3 D |
From 84.00€
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Item number: Cay14907-10
MeOSuc-Ala-Ala-Pro-Val-AMC (MeOSuc-AAPV-AMC) is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase. The methoxy succinyl (MeO-Suc) peptide AAPV is avidly hydrolyzed by these elastases but not by cathepsin G. The addition of 7-amino-4-methylcoumarin (AMC) generates a peptide of low...
Keywords: | I 1270, MeOSuc-AAPV-AMC, Methoxy Succinyl-Ala-Ala-Pro-Val-AMC,... |
Application: | Fluorogenic elastase substrate |
CAS | 72252-90-5 |
MW: | 627.7 D |
From 39.00€
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Item number: Cay27957-1
GW 311616A is an inhibitor of neutrophil elastase (IC50 = 100 nM). It is selective for neutrophil elastase (IC50 = 22 nM for the human enzyme) over trypsin, cathepsin G, and plasmin (IC50s = >100 µM for all), as well as chymotrypsin and tissue plasminogen activator (IC50s = >3 µM for both), in cell-free assays. GW...
Keywords: | (3S,3aS,6aR)-hexahydro-3-(1-methylethyl)-1-(methylsulfonyl)-4-[(2E)-1-oxo-4-(1-piperidinyl)-2-buten-1-yl]-pyrrolo[3,2-b]py... |
Application: | Neutrophil elastase inhibitor |
CAS | 197890-44-1 |
MW: | 434 D |
From 109.00€
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