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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay24889-500 | 500 µg | - |
6 - 10 business days* |
699.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Adrenomedullin (1-52) is a peptide with diverse biological activities. It belongs to the... more
Product information "Adrenomedullin (1-52) (human) (trifluoroacetate salt)"
Adrenomedullin (1-52) is a peptide with diverse biological activities. It belongs to the calcitonin family of peptides, which includes amylin (Cay-24274, Cay-24275), calcitonin gene-related peptide (Cay-24405, Cay-24725, Cay-24728), and calcitonin (Cay-24409, Cay-24410). Adrenomedullin (1-52) is expressed in pheochromocytomas, adrenal medulla, heart, lung, and kidney as well as human umbilical vein endothelial cells (HUVECs) and in human glomerular epithelial and hematopoietic cell lines. In vivo, adrenomedullin (1-52) (10-3,000 ng per animal) reverses increases in lobar arterial pressure induced by U-46619 (Cay-16450) in a dose-dependent manner in cats but has no effect on basal lobar arterial pressure or systemic arterial pressure. It reduces mechanical ventilation-induced lung injury and sepsis as well as liver and gut injury induced by ventilator-induced lung injury in a mouse model of pneumococcal pneumonia infection. Adrenomedullin (1-52) improves survival and inhibits cardiac tissue damage induced by doxorubicin (Cay-15007) in mice. Adrenomedullin (1-52) also reduces hyperoxia-induced right ventricular hypertrophy and artery thickness in a rat model of bronchopulmonary dysplasia.Formal Name: adrenomedullin (human), trifluoroacetate salt. Synonyms: ADM, AM. Molecular Formula: C264H406N80O77S3 . XCF3COOH. Formula Weight: 6028.7. Purity: >95%. Formulation: (Request formulation change), A lyophilized powder. Solubility: Water: 1 mg/ml. SMILES: NC([C@@H](NC(CNC([C@H](CCC(N)=O)NC([C@@H]1CCCN1C([C@H](CO)NC([C@@]([C@H](CC)C)([H])NC([C@H](CCCCN)NC([C@H](CO)NC([C@H](CCCNC(N)=N)NC([C@@H]2CCCN2C([C@@H](NC([C@H](C(C)C)NC([C@H](CC(N)=O)NC([C@@H](NC([C@H](CCCCN)NC([C@@H](NC([C@H](CCCCN)NC([C@@H](NC([C@@]([C@@H](C)O)([H])NC([C@@H](NC([C@H](CCC(N)=O)NC([C@@H](NC([C@@]([C@H](CC)C)([H])NC([C@H](CCC(N)=O)NC([C@@H](NC([C@@H](NC([C@H](CC(C)C)NC([C@H](CCCCN)NC([C@H](CCC(N)=O)NC([C@H](C(C)C)NC([C@@]([C@@H](C)O)([H])NC([C@@H](N3)CSSC[C@H](NC(CNC([C@@H](NC([C@H](CO)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC(CNC([C@H](CCC(N)=O)NC([C@@H](NC([C@H](CC(N)=O)NC([C@H](CC(N)=O)NC([C@@H](NC([C@H](CO)NC([C@H](CCC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@@H](N[H])CC4=CC=C(O)C=C4)=O)=O)=O)=O)CCSC)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)CC6=CC=CC=C6)=O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(NCC(N[C@]([C@@H](C)O)([H])C3=O)=O)=O)CC7=CC=CC=C7)=O)=O)=O)=O)=O)=O)=O)=O)C)=O)CC8=CN=CN8)=O)=O)=O)CC9=CC=C(O)C=C9)=O)=O)CC%10=CC=CC=C%10)=O)=O)CC(O)=O)=O)=O)CC(O)=O)=O)=O)CC(O)=O)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC%11=CC=C(O)C=C%11)=O.FC(F)(C(O)=O)F. InChi Code: InChI=1S/C264H406N80O77S3.C2HF3O2/c1-19-133(11)208(254(415)329-173(109-146-69-75-150(354)76-70-146)236(397)312-162(79-85-192(272)357)228(389)322-174(108-143-53-31-24-32-54-143)243(404)341-211(138(16)350)257(418)330-181(116-205(372)373)241(402)306-154(57-35-39-92-267)222(383)327-179(114-203(368)369)240(401)305-153(56-34-38-91-266)223(384)328-180(115-204(370)371)242(403)326-178(113-198(278)363)244(405)337-206(131(7)8)252(413)299-136(14)259(420)343-98-45-63-188(343)250(411)315-159(62-44-97-292-264(286)287)226(387)331-182(122-345)245(406)308-155(58-36-40-93-268)231(392)339-209(134(12)20-2)255(416)334-185(125-348)260(421)344-99-46-64-189(344)251(412)316-161(78-84-191(271)356)217(378)293-118-199(364)300-167(213(279)374)104-145-67-73-149(353)74-68-145)340-232(393)165(82-88-195(275)360)313-237(398)175(110-147-117-288-128-297-147)318-214(375)135(13)298-233(394)169(102-130(5)6)319-221(382)152(55-33-37-90-265)304-227(388)164(81-87-194(274)359)317-253(414)207(132(9)10)338-258(419)212(139(17)351)342-249(410)187-127-424-423-126-186(248(409)309-157(60-42-95-290-262(282)283)224(385)320-170(105-140-47-25-21-26-48-140)218(379)296-121-202(367)336-210(137(15)349)256(417)335-187)302-201(366)120-295-219(380)171(106-141-49-27-22-28-50-141)321-247(408)184(124-347)332-225(386)158(61-43-96-291-263(284)285)307-234(395)168(101-129(3)4)301-200(365)119-294-216(377)160(77-83-190(270)355)310-235(396)172(107-142-51-29-23-30-52-142)323-238(399)177(112-197(277)362)325-239(400)176(111-196(276)361)324-230(391)166(89-100-422-18)314-246(407)183(123-346)333-229(390)163(80-86-193(273)358)311-220(381)156(59-41-94-289-261(280)281)303-215(376)151(269)103-144-65-71-148(352)72-66-144,3-2(4,5)1(6)7/h21-32,47-54,65-76,117,128-139,151-189,206-212,345-354H,19-20,33-46,55-64,77-116,118-127,265-269H2,1-18H3,(H2,270,355)(H2,271,356)(H2,272,357)(H2,273,358)(H2,274,359)(H2,275,360)(H2,276,361)(H2,277,362)(H2,278,363)(H2,279,374)(H,288,297)(H,293,378)(H,294,377)(H,295,380)(H,296,379)(H,298,394)(H,299,413)(H,300,364)(H,30. InChi Key: YULATDANFPGQAF-XKBWIQTRSA-N.
Keywords: | Adrenomedullin (1-52)-NH2, adrenomedullin (human), trifluoroacetate salt |
Supplier: | Cayman Chemical |
Supplier-Nr: | 24889 |
Properties
Application: | Multifunctional peptide |
Conjugate: | No |
Species reactivity: | human |
MW: | 6028.7 D |
Formula: | C264H406N80O77S3 . XCF3COOH |
Purity: | >95% |
Format: | Solid |
Database Information
KEGG ID : | K12333 | Matching products |
UniProt ID : | P35318 | Matching products |
Gene ID | GeneID 133 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Signal Word: | Warning |
GHS Hazard Pictograms: |
|
H Phrases: | H361 |
P Phrases: | P201, P202, P280, P308+P313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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