83 products were found matching "K12333"!

Detection Range: 15.63-1000 pg/mL. Test Principle: Colorimetric method,ELISA,Sandwich. Sensitivity: 9.38 pg/mL. Protein function: Adrenomedullin/ADM and proadrenomedullin N-20 terminal peptide/PAMP are peptide hormones that act as potent hypotensive and vasodilatator agents (PubMed:8387282, PubMed:9620797). Numerous...

Adrenomedullin (13-52) is a truncated form of adrenomedullin (1-52) (Cay-24889). It induces nitric oxide-dependent relaxation of and inhibits release of angiotensin II (Cay-17150) and endothelin-1 (Cay-24127) from isolated rat aorta. In vivo, adrenomedullin (13-52) decreases mean arterial pressure (MAP) in...

Adrenomedullin (1-52) is a peptide with diverse biological activities. It belongs to the calcitonin family of peptides, which includes amylin (Cay-24274, Cay-24275), calcitonin gene-related peptide (Cay-24405, Cay-24725, Cay-24728), and calcitonin (Cay-24409, Cay-24410). Adrenomedullin (1-52) is expressed in...

Adrenomedullin (22-52) is a C-terminal fragment of adrenomedullin (1-52) (Cay-24889). In vitro, adrenomedullin (22-52) reduces basal corticosterone production in a mixture of rat adrenocortical and adrenomedulllary cells. It also reverses increases in ACTH-stimulated corticosterone production induced by...

Proadrenomedullin (N-20) (PAMP-20) is an endogenous peptide with hypotensive activity. It consists of the 20 N-terminal amino acids of proadrenomedullin and is found primarily in human adrenal medulla and pheochromocytoma tissue, with small amounts present in the heart, lung, liver, spleen, pancreas, kidney, small...

Adrenomedullin (11-50) is a truncated form of rat adrenomedullin. Intravenous administration of adrenomedullin (11-50) (3-10 µg/animal) decreases mean systemic arterial pressure in rats in a dose-dependent manner without affecting cardiac output. Cerebroventricular injection of adrenomedullin (11-50) (88 pmol)...

Adrenomedullin (1-50) is a peptide hormone with RNA expressed in rat adrenal glands, lung, kidney, heart, and spleen, as well as in the duodenum and submandibular glands. The rat amino acid sequence is similar to human adrenomedullin (1-52) (Cay-24889) but lacks two amino acids and contains six substitutions....

Proadrenomedullin (45-92) (MR-proADM) is a peptide that is comprised of amino acid residues 45-92 of preproadrenomedullin. MR-proADM has no effect on precontracted isolated cat pulmonary arterial rings when used at concentrations up to 10 µM, unlike adrenomedullin (1-52) (Cay-24889) and adrenotensin, which induce...

Proadrenomedullin (N-20) is a peptide comprised of amino acid residues 22-41 of rat preproadrenomedullin. The rat proadrenomedullin (N-20) sequence is similar to human proadrenomedullin (N-20) (Cay-27102) but contains three amino acid substitutions at residues 5, 6, and 8 of the human proadrenomedullin (N-20)...

Proadrenomedullin (N-20) is an endogenous peptide consisting of the 20 N-terminal amino acids of proadrenomedullin, which also corresponds to amino acids 22-41 of preproadrenomedullin. Proadrenomedullin (N-20) has been found in porcine adrenal medulla. The porcine and bovine proadrenomedullin (N-20) amino acid...