Osteoprotegerin, human recombinant

Osteoprotegerin, human recombinant
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
97597.1 1 mg - -

3 - 10 business days*

97597.10 10 µg - -

3 - 10 business days*

97597.50 50 µg - -

3 - 10 business days*

Human recombinant Osteoprotegerin produced in E.coli is a single, non-glycosylated, polypeptide... more
Product information "Osteoprotegerin, human recombinant"
Human recombinant Osteoprotegerin produced in E.coli is a single, non-glycosylated, polypeptide chain containing 174 amino acids and having a molecular mass of 20kDa. Osteoprotegerin acts as decoy receptor for rankl and thereby neutralizes its function in osteoclastogenesis. OPG inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local rankl/opg ratio. Osteoprotegerin may also play a role in preventing arterial calcification. May act as decoy receptor for trail and protect against apoptosis. Trail binding blocks the inhibition of osteoclastogenesis.
Keywords: OCIF, TNFRSF11B, Osteoprotegerin, Osteoclastogenesis inhibitory factor, Tumor necrosis factor receptor superfamily member 11B
Supplier: Biomol GmbH
Supplier-Nr: 97597


Application: Cell Culture
Conjugate: No
Expressed in: E.coli
Origin: Human
MW: 20000 D
Purity: >95%
Format: Lyophilized

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Shipping: +20°C (International: +20°C)
Our products are for laboratory research use only: Not for administration to humans!
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