Native Cytokines

The product of the AHSG gene is commonly referred to as fetuin in species other than the human. The first fetal plasma protein to be described was fetuin, which was purified from fetal and newborn calf serum by Pedersen in 1944. Fetuin was subsequently shown to be a very abundant plasma protein in fetal cattle,...

Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. (www.uniprot.org) Produced in submaxillary gland of grown mouse. Homodimer, non-glycosylated, polypeptide chain...

Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of...

EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity)....

Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (www.uniprot.org) Insulin Porcine is a two chain, glycosylated polypeptide chain containing 51 amino...

The heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro. (www.uniprot.org) Purified from bovine brain

Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent...

Human Acrp30 protein contains 244 amino acid having a molecular mass of 26.42kDa. Native adiponectin is isolated from human pooled sera and contains all HMW, MMW and LMW fractions. Adiponectin, also referred to as Acrp30, AdipoQ and GBP-28, is a recently discovered 244 amino acid protein, the product of the apM1...

Human APOA2 isolated from human HDL is a single, glycosylated, polypeptide chain having a molecular mass of 17.38kDa. APOA2 stabilizes the HDL structure by its relationship with lipids, and plays a role in the HDL metabolism. APOA2 is the 2nd most abundant protein of the high density lipoprotein particles. APOA2 is...

Mouse and rat beta-defensin-1 are synthesized from the 69-amino acid precursor. The mature peptide corresponds to amino acids 33-69. The sequence of this mature MBD-1 is: DQY KCL QHG GFC LRS SCP SNT KLQ GTC KPD KPN CCK S. This peptide was synthesized and disulfides were formed in their natural orientation....

Fetuin is a liver-produced negative acute phase protein composed of two subunits, the A and B chains Fetuin homologs have been identified in several species including rat, sheep, pig, rabbit, guinea pig, cattle, mouse and human. Multiple physiological roles for these homologs have been suggested, including ability...

Glia maturation factor gamma (GMF-gamma) is a cytokine-responsive protein in erythropoietin-induced and granulocyte-colony stimulating factor-induced hematopoietic lineage development. Also Glia maturation factor is a nerve growth factor implicated in nervous system development, angiogenesis and immune function....