Native Cytokines

Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (www.uniprot.org) Insulin Porcine is a two chain, glycosylated polypeptide chain containing 51 amino...

EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity)....

Human Acrp30 protein contains 244 amino acid having a molecular mass of 26.42kDa. Native adiponectin is isolated from human pooled sera and contains all HMW, MMW and LMW fractions. Adiponectin, also referred to as Acrp30, AdipoQ and GBP-28, is a recently discovered 244 amino acid protein, the product of the apM1...

Human APOA2 isolated from human HDL is a single, glycosylated, polypeptide chain having a molecular mass of 17.38kDa. APOA2 stabilizes the HDL structure by its relationship with lipids, and plays a role in the HDL metabolism. APOA2 is the 2nd most abundant protein of the high density lipoprotein particles. APOA2 is...

Mouse and rat beta-defensin-1 are synthesized from the 69-amino acid precursor. The mature peptide corresponds to amino acids 33-69. The sequence of this mature MBD-1 is: DQY KCL QHG GFC LRS SCP SNT KLQ GTC KPD KPN CCK S. This peptide was synthesized and disulfides were formed in their natural orientation....

The product of the AHSG gene is commonly referred to as fetuin in species other than the human. The first fetal plasma protein to be described was fetuin, which was purified from fetal and newborn calf serum by Pedersen in 1944. Fetuin was subsequently shown to be a very abundant plasma protein in fetal cattle,...

Fetuin is a liver-produced negative acute phase protein composed of two subunits, the A and B chains Fetuin homologs have been identified in several species including rat, sheep, pig, rabbit, guinea pig, cattle, mouse and human. Multiple physiological roles for these homologs have been suggested, including ability...

Glia maturation factor gamma (GMF-gamma) is a cytokine-responsive protein in erythropoietin-induced and granulocyte-colony stimulating factor-induced hematopoietic lineage development. Also Glia maturation factor is a nerve growth factor implicated in nervous system development, angiogenesis and immune function....

CXCL3/GROg is a small cytokine belonging to the CXC chemokine family. CXCL3 controls migration and adhesion of monocytes and mediates it effects on its target cell by interacting with a cell surface chemokine receptor called CXCR2. The three GRO cDNAs encode 107 amino acid precursor proteins from which the...

Human LEC (liver-expressed chemokine) also known as NCC-4 is a recently discovered CC chemokine. Recombinant Human LEC is a 11.2kDa protein containing 97 amino acid residues. Source: E.coli , Form: Sterile filtered solution lyophilized without additives. Stability: Lophilized protein is stable for a few weeks at...

Lipopolysaccharide-induced CXC chemokine (LIX), a 9.9kD protein, is a murine neutrophil-chemoattractant CXC chemokine. Biological Activity: 1. Determined by its ability to chemoattract human neutrophils using a concentration range of 10-100ng/ml., 2. Determined by its ability to chemoattract Murine lymphocytes using...

Human Macrophage-Derived Chemokine (MDC) is a unique member of the CC chemokine family. Human MDC is highly expressed in macrophages and in monocyte-derived dendritic cells, but not in monocytes, natural killer cells, or several lines of epithelial cells.