Recombinant Cytokines

Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells...

Basic fibroblast growth factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and...

Tumor necrosis factor is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages. TNF causes apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesis and viral...

Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 127 amino acids. The ED50 as determined by...

Induces cartilage and bone formation. (www.uniprot.org) Produced in E.coli. Homodimeric, non-glycosylated polypeptide chain containing 115 amino acids. The ED50 as determined by the cytolysis of MC3T3-E1 cells is less then 50 ng/ml.

Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a...

Authentic recombinant human protein, human cell expressed, which in general ensures proper folding, phosphorylation, disulfide bridge formation, proteolytic processing, and glycosylation. Endotoxin 0.04 EU/µg.

Authentic recombinant human protein, human cell expressed, which in general ensures proper folding, phosphorylation, disulfide bridge formation, proteolytic processing, and glycosylation.

Authentic recombinant human protein, human cell expressed, which in general ensures proper folding, phosphorylation, disulfide bridge formation, proteolytic processing, and glycosylation. Endotoxin < 1 EU/µg.

PProduced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. (www.uniprot.org)...

Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects...

Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B-...