Osteoprotegerin, Yeast, human recombinant (rHuOPG)

Osteoprotegerin, Yeast, human recombinant (rHuOPG)
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Item number Size Datasheet Manual SDS Delivery time Quantity Discount Price
94902.1 1 mg - -

1 - 10 business days

20 %
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94902.10 10 µg - -

1 - 10 business days

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70.00€
56.00€
94902.50 50 µg - -

1 - 10 business days

20 %
180.00€
144.00€
 
Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis.... more
Product information "Osteoprotegerin, Yeast, human recombinant (rHuOPG)"

Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis. (www.uniprot.org) Produced in yeast, containing 412 amino acid residues, including 180 residues from mature OPG (amino acids 22-201) and 232 residues from the Fc protein of human IgG1.

Keywords: TNFRSF11B, OPG, OCIF, Osteoclastogenesis inhibitory factor, TR1, MGC29565
Supplier: Biomol GmbH
Supplier-Nr: 94902.1

Properties

Application: Cell biology studies
Conjugate: No
Expressed in: Pichia pastoris
Origin: Human
MW: 46500 D
Purity: >90%
Format: Lyophilized

Database Information

KEGG ID : K05148 | Find alternatives
UniProt ID : O00300 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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