IL-1 alpha, Swine

Sequence: MSATYSFQSN MKYNFMRVIN HQCILNDARN QSIIRDPSGQ YLMAAVLNNL DEAVKFDMAA YTSNDDSQLP VTLRISETRL VLLKELPETP KTIKDETSLL FFWEKHGNMD YFKSAAHPKL FIATRQEKLV HMAPGLPSVT with polyhistidine tag at the C-terminus Endotoxin level: <0.1 EU per 1 µg of the protein by the LAL method. Protein function: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. [The UniProt Consortium]