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Fibroblast Growth Factor-19, His Tag, human recombinant (rHuFGF-19-His)
Product information "Fibroblast Growth Factor-19, His Tag, human recombinant (rHuFGF-19-His)"
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 206 amino acids. The amino acid sequence of the recombinant human FGF19 is 100% homologous to the amino acid sequence of the human FGF19 without signal sequence and contai