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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
348043.5 | 5 µg | - | - |
3 - 19 business days* |
410.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1... more
Product information "Fibroblast Growth Factor 19, active (FGF19), Recombinant, Human"
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. {ECO:0000269, PubMed:12815072, ECO:0000269, PubMed:16597617, ECO:0000269, PubMed:17623664, ECO:0000269, PubMed:19085950}. Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 150ng/ml, corresponding to a specific activity of ?6.7x10e3 IU/mg. Sequence: MRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK, Molecular Weight: 21.8kD, PubMed ID: 9931477, 10525310, 12975309, 15489334, 15340161, 12815072, 16597617, 17623664, 18829467, 19085950, 20094046, 14730967, 17339340, Gene Name: FGF19, UNQ334/PRO533, Swiss Prot: O95750, Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | FGF19, FGF-19, Fibroblast growth factor 19 |
Supplier: | United States Biological |
Supplier-Nr: | 348043 |
Properties
Conjugate: | No |
MW: | 21,8 |
Format: | Highly Purified |
Database Information
KEGG ID : | K22603 | Matching products |
UniProt ID : | O95750 | Matching products |
Gene ID | GeneID 9965 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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