Human recombinant AIMP1 fused with a 20 amino acid His tag at N-terminus produced in E.coli is a single, non-glycosylated, polypeptide chain containing 356 amino acids (1-336) and having a molecular mass of 39.2kDa (Molecular size on SDS-PAGE will appear higher). AIMP1 (EMPA2 or p43) is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of the AIMP1 cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. Furthermore, AIMP1 is involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells.
|Keywords:||Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Multisynthase complex auxiliary component p43, AIMP1, EMAP2, SCYE1, p43, EMAPII.|
|KEGG ID :||K15437 | Find alternatives|
|UniProt ID :||Q12904 | Find alternatives|
|Gene ID||GeneID 9255 | Find alternatives|
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