Other Cell-Based Assays

CCR3 or Chemokine (CC) receptor type 3, a key member of the GPCR family, is critically involved in various inflammatory and allergic conditions, including asthma, eosinophilic disorders, and certain autoimmune diseases, making it an important therapeutic target. Traditional methods for studying GPCRs often fail to...

CXCR2 or C-X-C motif chemokine receptor 2 belongs to the GPCR family, and plays a pivotal role in immune responses by mediating the effects of various chemokines. CXCR2 is implicated in various inflammatory, immune, and pathological conditions, including neutrophil recruitment, cancer progression, and angiogenesis,...

Nociceptin/Orphanin FQ Peptide Receptor (NOP) is a member of the opioid receptor family that is involved in regulating pain, anxiety, stress, and other physiological processes. Unlike classical opioid receptors, NOP signaling does not mediate typical opioid-induced analgesia, euphoria and respiratory depression,...

hDOR, also known as the Human Delta Opioid Receptor, is a key member of the G-protein coupled receptor (GPCR) family. It plays an essential role in modulating analgesia, mood regulation, and neuroprotection. hDOR is implicated in various conditions, including chronic pain, depression, and neurodegenerative...

Vasopressin receptor 2 (V2R), a key GPCR, regulates water homeostasis and fluid balance by activating adenylyl cyclase and increasing intracellular cAMP upon vasopressin binding. Dysregulation of V2R signaling is linked to conditions such as diabetes insipidus, hypertension, and heart failure. Traditional methods...

CCR2B or Chemokine (CC) receptor type 2B, a key member of the GPCR family, is implicated in a variety of inflammatory, autoimmune diseases, cancer, fibrosis, and other pathological conditions, making it a vital therapeutic target. Traditional methods for studying GPCRs often fail to address the signaling mechanisms...

CXCR1 or C-X-C motif chemokine receptor 1, a key member of the GPCR family, plays an essential role in the immune response and is associated with inflammatory and immune disorders, including neutrophil recruitment in conditions such as asthma, chronic obstructive pulmonary disease (COPD), and cancer metastasis,...

CXCR4, or C-X-C motif chemokine receptor 4, is a key member of the GPCR family that plays a critical role in immune system regulation, cell migration, and tissue homeostasis and is implicated in various pathological processes, including HIV entry, cancer metastasis, and inflammatory diseases, making it a significant...

Chemokine (CC) receptor type 1 (CCR1), a key member of the GPCR family, is implicated in various inflammatory and immune-related disorders, making it an important therapeutic target. Traditional methods for studying GPCRs often fail to address the signaling mechanisms of specific GPCRs like CCR1, which couple to...

CCR5 or Chemokine (CC) receptor type 5 is a member of the GPCR family that plays a crucial role in immune responses and is involved in the pathogenesis of various diseases, including HIV infection, where it serves as a co-receptor for viral entry. Additionally, CCR5 has been associated with inflammatory diseases,...

Dopamine receptor D1 (D1R) is a key member of the G-protein coupled receptor (GPCR) family, involved in several physiological processes, including motor control, reward, learning, and memory. Dysregulation of D1R signaling is implicated in various neurological disorders, such as Parkinson's disease, schizophrenia,...

Cayman's Adipolysis Assay Kit provides a complete assay for studying the lipolysis of triglycerides, from the differentiation of adipocyte-like cells to the quantitation of released glycerol. 3T3-L1 cells are differentiated using a common adipogenesis induction procedure to accumulate lipid droplets, and...