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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
040620-APC.200 | 200 µl | - | - |
3 - 19 business days* |
993.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene was identified as a tumor suppressor that is mutated in a large number of cancers at... more
Product information "Anti-phospho-PTEN (Tyr68) (PTEN, MMAC1, TEP1, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase"
This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. Applications: Suitable for use in Dot Blot, FLISA, Recommended Dilution: FLISA: 1:1,000, Dot blot 1:500, Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Keywords: | Anti-phospho-PTEN, Anti-phospho-MMAC1, EC=3.1.3.67, EC=3.1.3.48, EC=3.1.3.16, Anti-phospho-Phosphatase and tensin homolog, Anti-phospho-Mutated in multiple advanced cancers 1, Anti-phospho-Phosphatidylinositol 3,4 |
Supplier: | United States Biological |
Supplier-Nr: | 040620-APC |
Properties
Application: | FLISA, Dot Blot |
Antibody Type: | Polyclonal |
Conjugate: | APC |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Phospho-PTEN-Y68 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y68 of human PTEN. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K01110 | Matching products |
UniProt ID : | P60484 | Matching products |
Gene ID | GeneID 5728 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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