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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES5722.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES5722.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
developmental stage:Expressed in early stage of myeloid and erythroid... more
Product information "Anti-phospho-Lck BP-1 (Tyr378)"
developmental stage:Expressed in early stage of myeloid and erythroid differentiation.,function:Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.,PTM:Phosphorylated by LYN, rapidly after cross-linking of surface IgM on B-cells.,similarity:Contains 1 SH3 domain.,similarity:Contains 4 cortactin repeats.,subunit:Associates with the SH2 and SH3 domains of LCK. Binding to he LCK SH3 domain occurs constitutively, while binding to the LCK SH2 domain occurs only upon TCR stimulation. A similar binding pattern was observed with LYN, but not with FYN in which the FYN SH2 region associates upon TCR stimulation but the FYN SH3 region does not associate regardless of TCR stimulation. Directly associates with HAX1, through binding to its C-terminal region. Interacts with HS1BP3.,tissue specificity:Expressed only in tissues and cells of hematopoietic origin., Protein function: Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000,IHC-p 1:50-300, ELISA 2000-20000. Cellular localization: Membrane , Peripheral membrane protein . Cytoplasm . Mitochondrion .
Keywords: | Anti-phospho-p75, Anti-phospho-HS1, Anti-phospho-HCLS1, Anti-phospho-LckBP1, Anti-phospho-Hematopoietic lineage cell-specific protein, Anti-phospho-Hematopoietic cell-specific LYN substrate 1, Lck BP-1 (phospho Tyr378) rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES5722 |
Properties
Application: | WB, ELISA, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, rat, mouse, |
Immunogen: | Synthesized phospho-peptide around the phosphorylation site of human Lck BP-1 (phospho Tyr378) |
MW: | 78 kD |
Format: | Purified |
Database Information
KEGG ID : | K06106 | Matching products |
UniProt ID : | P14317 | Matching products |
Gene ID | GeneID 3059 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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