Anti-phospho-IFNAR1 (Ser535 / Ser539)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG52325.50	50 µl		-	-	6 - 14 business days*		592.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Component of the receptor for type I interferons, including interferons alpha,... more

Close menu

Product information "Anti-phospho-IFNAR1 (Ser535 / Ser539)"

Protein function: Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed:2153461, PubMed:7665574, PubMed:10049744, PubMed:14532120, PubMed:15337770, PubMed:21854986). Functions in general as heterodimer with IFNAR2 (PubMed:7665574, PubMed:10049744, PubMed:21854986). Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (PubMed:7665574, PubMed:21854986). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway. [The UniProt Consortium]

Keywords:	Anti-phospho-IFNAR, Anti-phospho-CRF2-1, Anti-phospho-IFNAR1, Anti-phospho-IFN-R-1, Anti-phospho-IFN-alpha/beta receptor 1, Anti-phospho-Type I interferon receptor 1, Anti-phospho-Interferon alpha/beta receptor 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG52325

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, rat (Expected: mouse, bovine, dog, primates, sheep)
Immunogen:	Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser535/539 conjugated to KLH
MW:	64 kD
Format:	Affinity Purified