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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay10009410-1 | 100 µl | - |
6 - 10 business days* |
564.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The activating transcription factor 2 (ATF2, also called CRE-BP1) binds to both AP-1 and CRE DNA... more
Product information "Anti-ATF2 (Phospho-Ser490,498)"
The activating transcription factor 2 (ATF2, also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins. ATF2 has been implicated in the transcriptional regulation of a number of genes including cytokines, cell cycle control, and apoptosis. Various forms of cellular stress, including inflammatory cytokines and UV irradiation, stimulate the transcriptional activity of ATF2. Stress induced ATF-dependent transcription is dependent on phosphorylation of ATF. Serine 490 and serine 498 are novel phosphorylation sites on ATF that have recently been identified. ATF2 is particularly abundant in the brain and the ATF2 family of transcription factors is considered an important substrate of signals upstream of the activation of genes associated with neuronal growth and differentiation. ATF expression has also been linked to depression in humans.Synonyms: Activating Transcription Factor 2. Immunogen: synthetic phosphopeptide corresponding to amino acid residues surrounding phospho-Ser490,498 of human ATF2. Formulation: (Request formulation change), Peptide affinity-purified antibody. Host: Rabbit. Applications: WB and IHC (frozen sections). Origin: Animal/Rabbit.
Keywords: | Activating Transcription Factor 2 |
Supplier: | Cayman Chemical |
Supplier-Nr: | 10009410 |
Properties
Application: | WB, IHC (frozen) |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | synthetic phosphopeptide corresponding to amino acid residues surrounding phospho-Ser490,498 of human ATF2 |
Format: | Solid |
Database Information
KEGG ID : | K04450 | Matching products |
UniProt ID : | P15336 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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