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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A305-177A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A305-177A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: E3 SUMO-protein ligase, has a preference for SUMO2 and SUMO3 and facilitates... more
Product information "Anti-ZNF451"
Protein function: E3 SUMO-protein ligase, has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins (PubMed:26524493, PubMed:26524494). Plays a role in protein SUMO2 modification in response to stress caused by DNA damage and by proteasome inhibitors (in vitro). Required for MCM4 sumoylation. Has no activity with SUMO1 (PubMed:26524493). Preferentially transfers an additional SUMO2 chain onto the SUMO2 consensus site 'Lys-11' (PubMed:26524493). Negatively regulates transcriptional activation mediated by the SMAD4 complex in response to TGF-beta signaling. Inhibits EP300- mediated acetylation of histone H3 at 'Lys-9' (PubMed:24324267). Plays a role in regulating the transcription of AR targets (PubMed:18656483). [The UniProt Consortium]
Keywords: | Anti-ZNF451, Anti-Zinc finger protein 451, Anti-E3 SUMO-protein ligase ZNF451, Anti-Coactivator for steroid receptors |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A305-177A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: mouse) |
Immunogen: | synthetic peptide. The epitope recognized by A305-177A-T maps to a region between residue 1011 to 1061 of human Zinc finger protein 451 using the numbering given in entry Q9Y4E5.2 (GeneID 26036). |
Format: | Antigen Affinity Purified |
Database Information
UniProt ID : | Q9Y4E5 | Matching products |
Gene ID | GeneID 26036 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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