Anti-USP11, clone 1220CT620.193.189

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG55818.100	100 µl		-	-	6 - 14 business days*		584.00€

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Protein function: Protease that can remove conjugated ubiquitin from target proteins and... more

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Product information "Anti-USP11, clone 1220CT620.193.189"

Protein function: Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains (PubMed:12084015, PubMed:15314155, PubMed:17897950, PubMed:19874889, PubMed:20233726, PubMed:24724799). Inhibits the degradation of target proteins by the proteasome (PubMed:12084015). Cleaves preferentially 'Lys-6' and 'Lys-63'-linked ubiquitin chains. Has lower activity with 'Lys-11' and 'Lys-33'-linked ubiquitin chains, and extremely low activity with 'Lys-27', 'Lys-29' and 'Lys-48'- linked ubiquitin chains (in vitro) (PubMed:24724799). Plays a role in the regulation of pathways leading to NF-kappa-B activation (PubMed:17897950, PubMed:19874889). Plays a role in the regulation of DNA repair after double-stranded DNA breaks (PubMed:15314155, PubMed:20233726). [The UniProt Consortium]

Keywords:	Anti-UHX1, Anti-USP11, Anti-Ubiquitin thioesterase 11, Anti-Deubiquitinating enzyme 11, Anti-Ubiquitin carboxyl-terminal hydrolase 11, Anti-Ubiquitin-specific-processing protease 11
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG55818

Properties

Application:	FC, WB
Antibody Type:	Monoclonal
Clone:	1220CT620.193.189
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	KLH-conjugated synthetic peptide around aa. 32-300 (C-terminus) of Human USP11
Format:	Purified