Anti-UchL1 (Clone: 31A3)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-36-3025-100 100 µg -

3 - 11 business days*

853.00€
 
UchL1 (ubiquitin C-terminal hydrolase), also known as PGP9.5 (protein gene product 9.5) and... more
Product information "Anti-UchL1 (Clone: 31A3)"
UchL1 (ubiquitin C-terminal hydrolase), also known as PGP9.5 (protein gene product 9.5) and PARK5, is a neuronal biomarker and ubquitin system protein.UchL1 is a highly conserved antibody and has shown that it is expressed in neurons and neuroendocrine cells in vertebrates where it comprises about 5-10% of soluble cytoplasmic proteins. A minor proportion of UchL1 in brain is tightly bound to the membrane. UchL1 antibody is also expressed in human oocytes and spermatogonia. It is important to note that the use of an antibody as a biomarker in this case does not imply that an antibody defines absolute tissue specificity. Rather, it means that PGP9.5 is expressed in neurons and neuroendrocine cells at significantly higher levels than in other cell types. Protein function: Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity. [The UniProt Consortium]
Keywords: Anti-UCHL1, Anti-PGP9.5, Anti-UCH-L1, Anti-PGP 9.5, EC=6.-.-.-, EC=3.4.19.12, Anti-Ubiquitin thioesterase L1, Anti-Neuron cytoplasmic protein 9.5, Anti-Ubiquitin carboxyl-terminal hydrolase isozyme L1, Monoclonal Antibody to UchL1 (Clone: 31A3)
Supplier: Abeomics
Supplier-Nr: 36-3025

Properties

Application: IHC, WB
Antibody Type: Monoclonal
Clone: 31A3
Conjugate: No
Host: Mouse
Species reactivity: rat, mouse, human (Expected: pig)
Immunogen: Native UchL1 (PGP9.5) protein from brain was used as immunogen to generate the antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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