Anti-UBE2O

Anti-UBE2O
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R33146-100UG 100 µg - -

3 - 10 business days*

755.00€
 
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s)... more
Product information "Anti-UBE2O"
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Ubiquitin-conjugating enzyme E2O Protein function: E2/E3 hybrid ubiquitin-protein ligase that displays both E2 and E3 ligase activities and mediates monoubiquitination of target proteins (PubMed:23455153, PubMed:24703950). Negatively regulates TRAF6-mediated NF-kappa-B activation independently of its E2 activity (PubMed:23381138). Acts as a positive regulator of BMP7 signaling by mediating monoubiquitination of SMAD6, thereby regulating adipogenesis (PubMed:23455153). Mediates monoubiquitination at different sites of the nuclear localization signal (NLS) of BAP1, leading to cytoplasmic retention of BAP1. Also able to monoubiquitinate the NLS of other chromatin- associated proteins, such as INO80 and CXXC1, affecting their subcellular location (PubMed:24703950). Acts as a regulator of retrograde transport by assisting the TRIM27:MAGEL2 E3 ubiquitin ligase complex to mediate 'Lys-63'-linked ubiquitination of WASH1, leading to promote endosomal F-actin assembly (PubMed:23452853). [The UniProt Consortium]
Keywords: Anti-UBE2O, Anti-KIAA1734, Anti-Ubiquitin-protein ligase O, Anti-Ubiquitin carrier protein O, Anti-Ubiquitin-conjugating enzyme E2 O, Anti-Ubiquitin-conjugating enzyme E2-230K, Anti-Ubiquitin-conjugating enzyme E2 of 230 kDa, UBE2O Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: R33146

Properties

Application: IHC, ELISA (peptide)
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Species reactivity: human
Immunogen: Amino acids ALLEAGMPECTEDK were used as the immunogen for this UBE2O antibody.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-UBE2O"
Write a review
or to review a product.
Viewed