Anti-TXNIP

Anti-TXNIP
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-229A-T 10 µl (10 µg) -

3 - 9 business days

125.00€
A303-229A 100 µl (100 µg) -

3 - 9 business days

430.00€
 
Protein function: May act as an oxidative stress mediator by inhibiting thioredoxin activity or... more
Product information "Anti-TXNIP"
Protein function: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over- expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1). [The UniProt Consortium]
Keywords: Anti-VDUP1, Anti-TXNIP, Anti-Thioredoxin-binding protein 2, Anti-Thioredoxin-interacting protein, Anti-Vitamin D3 up-regulated protein 1
Supplier: Bethyl Laboratories
Supplier-Nr: A303-229A-T

Properties

Application: IP, IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human (Expected: Rat)
Immunogen: synthetic peptide. The epitope recognized by A303-229A-T maps to a region between residue 300 and 350 of human Thioredoxin Interacting Protein using the numbering given in entry NP_006463.3 (GeneID 10628).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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