Anti-TXNIP

Anti-TXNIP
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-17496.20 20 µl -

7 - 16 business days*

71.00€
E-AB-17496.60 60 µl -

7 - 16 business days*

143.00€
E-AB-17496.120 120 µl -

7 - 16 business days*

238.00€
E-AB-17496.200 200 µl -

7 - 16 business days*

396.00€
 
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its... more
Product information "Anti-TXNIP"
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1). Protein function: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over- expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1). [The UniProt Consortium]
Keywords: Anti-TXNIP, Anti-VDUP1, Anti-Thioredoxin-binding protein 2, Anti-Thioredoxin-interacting protein, Anti-Vitamin D3 up-regulated protein 1, TXNIP Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-17496

Properties

Application: IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Synthetic peptide of human TXNIP
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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