Anti-TRPA1 (Transient Receptor Potential Cation Channel Subfamily A Member 1, Ankyrin-like with Tran

Anti-TRPA1 (Transient Receptor Potential Cation Channel Subfamily A Member 1, Ankyrin-like with Tran
Item number Size Datasheet Manual SDS Delivery time Quantity Price
T8666-12C.25 25 µl - -

3 - 19 business days*

353.00€
T8666-12C.100 100 µl - -

3 - 19 business days*

616.00€
 
Transient receptor potential ion channels (TRPCs) are a superfamily of six transmembrane... more
Product information "Anti-TRPA1 (Transient Receptor Potential Cation Channel Subfamily A Member 1, Ankyrin-like with Tran"
Transient receptor potential ion channels (TRPCs) are a superfamily of six transmembrane segment-spanning, gated cation channels. TRPA1 is a TRP-related channel that responds to cold temperatures and pungent compounds and plays a role in both nociceptor and hair cell transduction. It is a transformation-associated gene product in lung epithelia, whereas its protein distribution is primarily restricted to sensory neurons. Blocking TRPA1 may be a therapeutic target for treating cold hyperalgesia caused by inflammation and nerve damage. It is now known that TRPA1 protein is also widely expressed outside of the CNS and is dys-regulated during oncogenic transformation. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 2ug/ml, Immunohistochemistry (Paraffin): 1:100-1:250, Immunohistochemistry (Frozen): 0.5-1.0ug/ml, Optimal dilutions to be determined by the researcher. Positive Control: Human brain membrane fraction, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: T8666-12C

Properties

Application: IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: A synthetic peptide made to a region within the N-terminus (residues 1-100) of the human TRPA1 protein. [Swiss-Prot# O75762]. Homology: 100% with human. 69% with mouse and rat.
Purity: Purified by peptide immunoaffinity chromatography.
Format: Affinity Purified

Database Information

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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