Anti-TPMT

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG57754.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine (also... more

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Product information "Anti-TPMT"

Protein function: Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine (also called mercaptopurine, 6-MP or its brand name Purinethol) and 6-thioguanine (also called tioguanine or 6- TG) using S-adenosyl-L-methionine as the methyl donor (PubMed:657528, PubMed:18484748). TPMT activity modulates the cytotoxic effects of thiopurine prodrugs. A natural substrate for this enzyme has yet to be identified. [The UniProt Consortium]

Keywords:	Anti-TPMT, Anti-Thiopurine methyltransferase, Anti-Thiopurine S-methyltransferase
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG57754

Properties

Application:	ICC, IF, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse)
Immunogen:	Recombinant funsion protein around aa. 1-245 of Human TPMT (NP_000358.1)
MW:	28 kD
Format:	Affinity Purified