Anti-TORC2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A300-638A-T	10 µl (2 µg)		-		2 - 8 business days*		165.00€
A300-638A	100 µl		-		2 - 8 business days*		586.00€

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Protein function: Transcriptional coactivator for CREB1 which activates transcription through... more

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Product information "Anti-TORC2"

Protein function: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). [The UniProt Consortium]

Keywords:	Anti-CRTC2, Anti-TORC2, Anti-TORC-2, Anti-Transducer of CREB protein 2, Anti-CREB-regulated transcription coactivator 2, Anti-Transducer of regulated cAMP response element-binding protein 2
Supplier:	Bethyl Laboratories
Supplier-Nr:	A300-638A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: orangutan, rhesus monkey, gorilla, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A300-638A-T maps to a region between residues 475 and 500 of human Transducer of Regulated cAMP Responsive Element-Binding Protein (CREB) 2 using the numbering given in entry NP_859066.1 (GeneID 200186).
Format:	Antigen Affinity Purified