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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V7245SAF-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
1 mg/ml in sterile PBS, BSA free, sodium azide free. This mAb recognizes a 170kDa protein which... more
Product information "Anti-TOP2A, clone TPM2A-1"
1 mg/ml in sterile PBS, BSA free, sodium azide free. This mAb recognizes a 170kDa protein which is identified as Topoisomerase IIa, and shows no cross-reaction with Topoisomerase IIb or I. Topo IIa plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells. Topo IIa is also implicated in drug resistance of tumor cells. Protein function: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation. [The UniProt Consortium]
Keywords: | Anti-TOP2, Anti-TOP2A, EC=5.99.1.3, Anti-DNA topoisomerase 2-alpha, Anti-DNA topoisomerase II, alpha isozyme, TOP2A Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V7245SAF |
Properties
Application: | WB, FC, IF, IHC |
Antibody Type: | Monoclonal |
Clone: | TPM2A-1 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human. others not tested |
Immunogen: | Human partial recombinant protein was used as the immunogen for this TOP2A antibody. |
Format: | Purified |
Database Information
KEGG ID : | K03164 | Matching products |
UniProt ID : | P11388 | Matching products |
Gene ID | GeneID 7153 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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