Anti-TOM70 (KIAA0719, Mitochondrial Precursor Proteins Import Receptor, Translocase of Outer Membran

Anti-TOM70 (KIAA0719, Mitochondrial Precursor Proteins Import Receptor, Translocase of Outer Membran
Item number Size Datasheet Manual SDS Delivery time Quantity Price
T8064-18.100 100 µl - -

3 - 19 business days*

498.00€
 
Functional mitochondria require up to 1000 proteins to function properly, with 99% synthesized as... more
Product information "Anti-TOM70 (KIAA0719, Mitochondrial Precursor Proteins Import Receptor, Translocase of Outer Membran"
Functional mitochondria require up to 1000 proteins to function properly, with 99% synthesized as precursors in the cytoplasm and transported into the mitochondria with the aid of cytosolic chaperones and mitochondrial translocators (import components). Proteins to be imported are chaperoned to the mitochondria by the cytosolic heat shock protein (cHSP70) and are immediately pursued by Translocators of the Outer Membrane (TOMs), followed by transient interactions of the unfolded proteins with Translocators of the Inner Membrane (TIMs). TOMM70A is ubiquitously expressed in human tissues and localizes in the mitochondria. TOMM70A could play a significant role in the import of nuclear-encoded mitochondrial proteins with internal targeting sites such as ADP/ATP carriers and the uncoupling proteins. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Positive Control: Purified mitochondrial extracts and HeLa whole cell extract. , Cellular Localization: Mitochondrial, multi-pass membrane. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: United States Biological
Supplier-Nr: T8064-18

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: A synthetic peptide made to a region within residues 1-100 of the human protein. [Swiss-Prot# O94826]. Homology: 100% with human, rat, and mouse proteins.
Purity: Purified by Protein A affinity chromatography.
Format: Affinity Purified

Database Information

Handling & Safety

Storage: -20°C (-20°C Glycerol)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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