Anti-Thymidylate Synthase, clone TS106

Anti-Thymidylate Synthase, clone TS106
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3162IHC-7ML 7 ml - -

3 - 10 business days

Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. It... more
Product information "Anti-Thymidylate Synthase, clone TS106"
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. It recognizes a protein of 36kDa, identified as Thymidylate Synthase (TS) (EC TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas. Protein function: Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. [The UniProt Consortium]
Keywords: Anti-TS, Anti-TYMS, Anti-TSase, EC=, Anti-Thymidylate synthase, Thymidylate Synthase Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3162IHC-7ML


Application: IHC
Antibody Type: Monoclonal
Clone: TS106
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Recombinant human protein was used as the immunogen for this Thymidylate Synthase antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-Thymidylate Synthase, clone TS106"
Write a review
or to review a product.