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This gene encodes a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. This gene plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. Protein function: Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes. Seems to also mediate the transcription of NF1. Does not bind the TATA box. [The UniProt Consortium]
Keywords:
Anti-TLF, Anti-STUD, Anti-TBPL1, Anti-TBP-like factor, Anti-TBP-like protein 1, Anti-TBP-related protein, Anti-TBP-related factor 2, Anti-21 kDa TBP-like protein, Anti-Second TBP of unique DNA protein, Anti-TATA box-binding protein-like protein 1, TBPL1 P
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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