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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
S7975-14C.50 | 50 µg | - | - |
3 - 19 business days* |
779.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
SDF-1 alpha, otherwise known as CXCL12a, is a 68 amino acid stromal cell derived CXC chemokine,... more
Product information "Anti-Stromal Cell Derived Factor 1 alpha (SDF1 alpha, SDF1a, SDF-1a, Chemokine (C-X-C Motif) Ligand"
SDF-1 alpha, otherwise known as CXCL12a, is a 68 amino acid stromal cell derived CXC chemokine, which arises from alternative splicing of the SDF-1 gene. The two isoforms, SDF-1 alpha and SDF-1 beta, share an identical amino acid sequence, except for an additional four residues in the C-terminal region of the beta isoform. SDF-1 binds with high-affinity to the G protein-coupled receptor CXCR4 (fusin) and acts as a chemoattractant for T and B lymphocytes, monocytes and migratory neurons, and is a vital factor in hematopoiesis and angiogenesis. By competitively binding to CXCR4, SDF-1 acts as an inhibitor for the CXCR4-mediated entry of HIV-1 virus into target T-cells, and the SDF-1-CXCR4 interaction is important for the regulation of trafficking of normal and malignant stem cells. , Applications:, Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 0.15-0.3ug/ml, Western Blot: 0.1-0.2ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | Anti-hSDF-1, Anti-SDF-1-beta(3-72), Anti-SDF-1-alpha(3-67), Anti-C-X-C motif chemokine 12, Anti-Stromal cell-derived factor 1, Anti-Intercrine reduced in hepatomas, Anti-Pre-B cell growth-stimulating factor |
Supplier: | United States Biological |
Supplier-Nr: | S7975-14C |
Properties
Application: | ELISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | Biotin |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Recombinant human SDF-1 alpha. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K10031 | Matching products |
UniProt ID : | P48061 | Matching products |
Gene ID | GeneID 6387 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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