Anti-STIM2

Anti-STIM2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with STIM2 from other sources has not been determined. Protein function: Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP. [The UniProt Consortium]