Anti-STIM1

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Discount	Price
ARG56839.50	50 µg		-	-	6 - 14 business days*		30 %	520.00€ 364.00€

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Protein function: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx... more

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Product information "Anti-STIM1"

Protein function: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores (PubMed:15866891, PubMed:16005298, PubMed:16208375, PubMed:16537481, PubMed:16733527, PubMed:16766533, PubMed:16807233, PubMed:18854159, PubMed:19249086, PubMed:22464749, PubMed:24069340, PubMed:24351972, PubMed:24591628, PubMed:26322679, PubMed:25326555). Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release- activated Ca(2+) (CRAC) channel subunit ORAI1 (PubMed:16208375, PubMed:16537481). Involved in enamel formation (PubMed:24621671). Activated following interaction with TMEM110/STIMATE, leading to promote STIM1 conformational switch (PubMed:26322679). [The UniProt Consortium]

Keywords:	Anti-STIM1, Anti-Stromal interaction molecule 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG56839

Properties

Application:	IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: rat)
Immunogen:	Synthetic peptide around 24 aa (C-terminus) of Human STIM1
MW:	59, 75, 87 kD
Format:	Antigen Affinity Purified