Anti-Semaphorin 5A

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-R33409-100UG	100 µg		-	-	3 - 10 business days*		755.00€

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0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s)... more

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Product information "Anti-Semaphorin 5A"

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: SEMA5A Protein function: Bifunctional axonal guidance cue regulated by sulfated proteoglycans, attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis. [The UniProt Consortium]

Keywords:	Anti-SEMAF, Anti-Sema F, Anti-SEMA5A, Anti-Semaphorin-F, Anti-Semaphorin-5A, Semaphorin 5A Antibody
Supplier:	NSJ Bioreagents
Supplier-Nr:	R33409

Properties

Application:	IHC, ELISA (peptide)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	human
Immunogen:	Amino acids DEATKKACYSKGKS were used as the immunogen for this Semaphorin 5A antibody. The amino acid sequence used as immunogen is from the extracellular portion of the protein.
Format:	Purified