Anti-Semaphorin 5A, Internal

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG64000.100	100 µg		-	-	6 - 14 business days*		784.00€

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Protein function: Bifunctional axonal guidance cue regulated by sulfated proteoglycans,... more

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Product information "Anti-Semaphorin 5A, Internal"

Protein function: Bifunctional axonal guidance cue regulated by sulfated proteoglycans, attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis. [The UniProt Consortium]

Keywords:	Anti-SEMAF, Anti-Sema F, Anti-SEMA5A, Anti-Semaphorin-F, Anti-Semaphorin-5A
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG64000

Properties

Application:	ELISA, IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	human (Expected: mouse, rat, canine, bovine)
Immunogen:	DEATKKACYSKGKS
Format:	Ammonium Sulfate Precipitated