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This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of... more
Product information "Anti-SDHA"
This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Protein function: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (PubMed:24781757). Can act as a tumor suppressor (PubMed:20484225). [The UniProt Consortium]
Keywords: | Anti-Fp, Anti-SDHA, Anti-SDH2, Anti-Flavoprotein subunit of complex II, Anti-Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, SDHA Polyclonal Antibody |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-60756 |
Properties
Application: | WB, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Recombinant protein of human SDHA |
Database Information
KEGG ID : | K00234 | Matching products |
UniProt ID : | P31040 | Matching products |
Gene ID | GeneID 6389 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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