Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10006373-1 1 each -

3 - 10 business days*

Sphingosine-1-phosphate (S1P) exerts its activity by binding to five distinct G-protein-coupled... more
Product information "Anti-S1P3"
Sphingosine-1-phosphate (S1P) exerts its activity by binding to five distinct G-protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8. S1P3 couples to Gi/o-ERK, Gq-PLC, and G12/13-Rho axes to mediate S1P-induced cell proliferation, survival, migration, and related signaling events. S1P3 is widely expressed in various tissues, suggesting diverse physiological functions of this receptor. The human and mouse S1P3 have 378 amino acids with an estimated molecular weight of 42 kDa. Glycosylation at the N-terminal extracellular domain may cause the protein to migrate at different positions in SDS-PAGE. Cayman's S1P3 Polyclonal Antibody can be used for immunocytochemistry and Western blot applications. The antibody recognizes S1P3 at 47 kDa from human, mouse, and rat samples. Liver and heart tissues display 2-3 bands between 40-50 kDa, possibly due to different degree of glycosylation.
Keywords: Anti-EDG3, Anti-S1P3, Anti-S1PR3, Anti-S1P receptor 3, Anti-S1P receptor Edg-3, Anti-Sphingosine 1-phosphate receptor 3, Anti-Sphingosine 1-phosphate receptor Edg-3, Anti-Endothelial differentiation G-protein coupled receptor 3
Supplier: Cayman Chemical
Supplier-Nr: 10006373-1


Application: ICC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Immunogen: human S1P3 amino acids 12-25 (VRGNETLREHYQYV)
Format: Solid

Database Information

KEGG ID : K04290 | Find alternatives
UniProt ID : Q99500 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319, H335
P Phrases: P261, P264, P271, P280, P312, P321, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501
Our products are for laboratory research use only: Not for administration to humans!
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